Effectiveness of Misoprostol for Induction of First-Trimester Miscarriages Experience at a single tertiary care centre in Oman
Journal Title: Sultan Qaboos University Medical Journal - Year 2015, Vol 15, Issue 4
Abstract
Objectives: Non-invasive methods of inducing a miscarriage are now considered an effective alternative to surgical evacuation (dilatation and curettage). Tis study aimed to evaluate the effectiveness of misoprostol in the termination of frst-trimester miscarriages. Methods: Tis prospective study was conducted between October 2009 and September 2010 and assessed all patients admitted to the Royal Hospital in Muscat, Oman, for the termination of frst-trimester miscarriages during the study period. All patients received misoprostol and the rates of successful termination were measured. Patient satisfaction was assessed using a short questionnaire. Results: A total of 290 women were included in the study. Termination with misoprostol was successful in 61.38% of the subjects. Of the remaining subjects requiring additional surgical evacuation (n = 112), 58.93% required evacuation due to failed termination with misoprostol and 65.18% underwent early evacuation (≤24 hours since their last misoprostol dose). Te majority of patients experienced no side-effects due to misoprostol (89.66%). Pain was controlled with simple analgesics in 70.00% of the subjects. A high satisfaction rate (94.83%) with the misoprostol treatment was reported. Conclusion: Misoprostol was a well-tolerated drug which reduced the rate of surgical evacuation among the study subjects. Tis medication can therefore be used safely in the management of incomplete miscarriages.
Authors and Affiliations
Qamariya Ambusaidi | Department of Obstetrics & Gynaecology, Royal Hospital, Muscat, Oman, Anita Zutshi| Department of Obstetrics & Gynaecology, Royal Hospital, Muscat, Oman
Keywords
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