Effectiveness of predicting outcome in septic shock in critically ill children by assessing serum lactate levels
Journal Title: Pediatric Review: International Journal of Pediatric Research - Year 2016, Vol 3, Issue 1
Abstract
Background and Aims: Hyperlactatemia at the time of admission is a documented risk factor for mortality in critically ill adult patients. However, the significance of lactate measurement at admission for mortality in critically ill children remains uncertain. This study evaluated the predictive value of blood lactate levels at the time of admission and determined the cut-off values for predicting in-hospital mortality in the critically ill children. Materials and Methods: A total of 60 children with diagnosis of sepsis admitted to PICU of a tertiary care hospital were included in the study. PRISM III score and demographic characteristics of all children were recorded. Serum lactate levels were measured at 0-3, 12 and 24 h of PICU admission. The outcome like survival or death was correlated with serum lactate levels. Results: Septic shock was the most common type of shock and had highest mortality. Lactate levels were significantly higher in non survivors in comparison to survivors. A lactate value of more than 5 mmol/l at 0-3, 12 and 24h of PICU admission had increased mortality. Conclusions: A high blood lactate level at admission is independently associated with higher in-hospital mortality in the critically ill children.
Authors and Affiliations
Jasashree Choudhury, Sidharth Sraban Routray
Keywords
Related Articles
- EP ID EP223126
- DOI 10.17511
- Views 214
- Downloads 0
Patterns of health care for children with asthma: A qualitative study
Background: Many children across the world, struggle with asthma, especially when the condition worsens due to lack of adherence to treatment strategies, the reason for which however may not be completely understood. Hen...
Interpretation of low birth weight babies by anthropometric measurements in South India
Introduction: Low birth weight is seen most commonly in developing countries. In India majority of births are conducted at home by the Traditional Birth Attendants (TBA) or relatives, where the estimation of birth weight...
Evaluation of acid base status and outcome of neonatal respiratory distress
Objective: Both pulmonary and extra pulmonary causes could present as tachypnea and respiratory distress. We have planned a study to evaluate acid base status and outcome of neonatal respiratory distress. Methods: A pros...
Socioeconomic determinants of severe anemia and assessment for iron and vitamin B12 deficiency among anemic adolescents
Background: Adolescence is the period of most rapid growth due to which they face serious nutritional challenges and make them more vulnerable to anemia. Anemia in the adolescence has a negative effect on their growth &...
Screening of high risk neonates for congenital heart defects: A study in level III neonatal intensive care unit
Introduction: Congenital heart defects are most common birth defects representing a major global health problem. So, early screening of high risk newborns for congenital heart defects is essential foe early intervention...