Effectiveness of predicting outcome in septic shock in critically ill children by assessing serum lactate levels
Journal Title: Pediatric Review: International Journal of Pediatric Research - Year 2016, Vol 3, Issue 1
Abstract
Background and Aims: Hyperlactatemia at the time of admission is a documented risk factor for mortality in critically ill adult patients. However, the significance of lactate measurement at admission for mortality in critically ill children remains uncertain. This study evaluated the predictive value of blood lactate levels at the time of admission and determined the cut-off values for predicting in-hospital mortality in the critically ill children. Materials and Methods: A total of 60 children with diagnosis of sepsis admitted to PICU of a tertiary care hospital were included in the study. PRISM III score and demographic characteristics of all children were recorded. Serum lactate levels were measured at 0-3, 12 and 24 h of PICU admission. The outcome like survival or death was correlated with serum lactate levels. Results: Septic shock was the most common type of shock and had highest mortality. Lactate levels were significantly higher in non survivors in comparison to survivors. A lactate value of more than 5 mmol/l at 0-3, 12 and 24h of PICU admission had increased mortality. Conclusions: A high blood lactate level at admission is independently associated with higher in-hospital mortality in the critically ill children.
Authors and Affiliations
Jasashree Choudhury, Sidharth Sraban Routray
Keywords
Related Articles
- EP ID EP223126
- DOI 10.17511
- Views 203
- Downloads 0
Role of cord blood bilirubin and albumin levels as predictors of subsequent hyperbilirubinemia in newborns
Introduction: Neonatal hyperbilirubinemia is one of the most common problems in term and preterm babies. Development of hyperbilirubinemia in neonates is fretful for the parents and a concern for the pediatrician too. He...
Langerhans cell sarcoma presenting as a mediastinal mass in a young infant: a case report
Langerhans Cell Sarcoma is an extremely rare disease. Its manifestations vary though skin, lymph-node and bone involvement are most commonly reported. It is an aggressive disease with a poor outcome. We report a six-week...
Type II hypersensitivity and trimethoprim-sulfamethoxazole
Type II hypersensitivity reaction is an unusual response to trimethoprim-sulfamethoxazole.We discuss a case of rash and pancytopenia immediately following the use of trimethoprim-sulfamethoxazole in an adolescent female.
Clinical and epidemiological study of scorpion sting envenomation at a teaching hospital in rural Telangana
Introduction: Scorpions have adapted to diverse environments and are mainly found in tropical and sub- tropical countries, between latitude 50 N and 50 S. Scorpion stings are primarily due to accidental contact with scor...
Atypical Presentation of Celiac Disease: A Case Report
Celiac disease is a chronic inflammatory immune-mediated condition associated with small intestinal injury triggered by gluten present in wheat, barley and rye, leading to malabsorption of different nutrients. Usually it...