Prognostic significance of total platelet count with PICU outcome
Journal Title: Pediatric Review: International Journal of Pediatric Research - Year 2016, Vol 3, Issue 6
Abstract
Background: Platelets in addition to their contribution in hemostasis are inflammatory cells having important role in host defense and can be of prognostic significance. Aim: Present study aims to evaluate the relationship of platelet, leucocyte count and C– reactive protein with outcome of cases admitted to Pediatric Intensive Care Unit (PICU). Material and Method: A prospective cohort study of 84 patients admitted for at least 3 days in the PICU at Institute of Medical Sciences and SUM Hospital, Bhubaneswar, India was undertaken from August 2015 to February 2016. Patient data related to socio-demographic profile, patient history, clinical features and investigational findings were recorded. Results: The mean platelet count on day of admission was 6.13 lakhs/cumm which decreased during the stay and showed significant positive correlation with the duration of PICU stay and death outcome. The change in platelet count during stay also showed significant association with death outcome. Significant correlation was observed between total leucocyte count and C-reactive protein with duration of stay. Also duration of stay is significantly associated with the death outcome. Conclusion: Platelet, leucocyte and C- reactive protein status on day of admission significantly correlates with duration of stay and death as outcome. Decreased platelet count during stay necessitates thorough evaluation of cases.
Authors and Affiliations
Swarup Kumar Bisoi, Mamata Devi Mohanty
Keywords
Related Articles
- EP ID EP225042
- DOI 10.17511
- Views 130
- Downloads 0
Quality of life in children with bronchial asthma
Introduction: Bronchial asthma is one of the most common childhood diseases. It imposes significant burden on children’s health related quality of life despite the availability of effective and safe treatment. So, this s...
A study on intima- media thickness of carotid artery in children withnephrotic syndrome: a cross sectional study
Introduction: Atherosclerosis is one of the complications of Nephrotic syndrome. It is due to frequent exposure to hyperlipidemia, hypertension, and hypoproteinemia, steroid and immunosuppressive therapy may also contrib...
A study on the types of dehydration and serum sodium level in infants and young children at the time of hospital admission with acute diarrhea in rural area of Jharkhand
Objectives: This study was done to know the incidence of different type of dehydration clinically in acute watery diarrhea (mild, moderate and severe) along with serum sodium level (isonatraemic, hyponatraemic, hypernatr...
Management of tongue-tie in children: a case report
Introduction: tongue-tie or ankyloglossia, is a congenital condition that results when the inferior lingual frenulum is too short and is attached to the tip of the tongue, limiting its normal movements. The restriction...
Correlation of platelet count and platelet indices with neonatal sepsis-diagnostic and prognostic indicator
Introduction: To evaluate variations in platelet count and platelet indices- mean platelet volume (MPV) and platelet distribution width (PDW) in neonatal sepsis. Methodology: This study was conducted over a period of one...