Effectiveness of Ropivacaine versus Levobupivacaine for Spinal Anaesthesia and Analgesia in Lower Limb Surgery
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 2
Abstract
Introduction: Newer local anaesthetic amides Ropivacaine and Levobupivacaine have gained popularity for spinal anaesthesia due to lower cardiotxicity and neurotoxicity. In this prospective, randomized double blind study we compare the effects of intrathecal isobaric ropivacaine 0.75% and levobupivacaine 0.5% in regards to the onset, regression, duration of sensory and motor blockade and also their hemodynamic stability, analgesic effect, and surgeon’s & patient’s satisfaction in term of surgical anaesthesia. Material and Methods: 68 patients of ASA1 to ASA3 physical status scheduled for lower limb surgery under spinal anaesthesia were recruited and randomized into Group L and Group R. Group L received 3ml of 0.5% Levobupivacaine and Group R received 3ml of 0.75% Ropivacaine intrathecally. Sensory & motor block onset, regression and hemodynamics were noted intraoperatively. Total duration of blockade and analgesia were noted postoperatively. Results: Group L had faster onset and longer duration of sensory and motor block with shorter motor regression time in comparison to Group R thus not hampering mobilization .Group L also had a longer time to first rescue analgesia and higher degree of patient’s and surgeon’s satisfaction in terms of surgical anaesthesia and were more hemodynamically stable in comparison to Group R. Conclusion: Both Ropivacaine and Levobupivacaine have desirable blocking property and can be used for lower limb surgery. Levobupivacaine provides more effective anaesthesia in term of onset, duration and longer period of post operative analgesia with lesser side effects and better patient’s and surgeon’s satisfaction in comparison to Ropivacaine.
Authors and Affiliations
Dr Alpa M Patel
Keywords
Related Articles
- EP ID EP506243
- DOI -
- Views 65
- Downloads 0
Etiological Factors Associated in Fever with Thrombocytopenia: A Clinical Study
Objective: This study was conducted to investigate factors associated in fever with thrombocytopenia Patients and Methods: The present observational study was done on 200 patients attending Medicine department, Medical C...
Anemia in Patients with Type 2 Diabetes in Absence of Renal Impairment
Objectives: this study aims to determine the prevalence of anemia in patients with type 2 diabetes in absence of renal impairment and its association with microalbuminuria and estimated glomerular filtration rate (eGFR)....
Relationship between Serum Vitamin D Level and Disease Activity in Rheumatoid Arthritis
Introduction: Vitamin D is a fat soluble vitamin. Main source of vitamin D is de novo synthesis in the skin by ultraviolet B rays of sunlight. The active metabolite of vitamin D is the 1,25-dihydroxyvitaminD3(1,25(OH)2 D...
Role of C-Reactive Proteins as a Diagnostic & Prognostic Indicator In Neonatal Sepsis
Aims and objectives 1) To assess role of CRP as a promising marker in diagnosis of neonatal sepsis. 2) To determine the utility of CRP as a prognostic indicator in neonatal sepsis. Study Design: This was an observational...
Paroxysmal Cold Hemoglobinuria: A Rare Case Presentation
Paroxysmal cold hemoglobinuria (PCH) is a rare cause of acquired autoimmune hemolytic anaemia (AIHA) commonly seen in children post viral infections caused by complement dependent cold acting autoantibodies that produce...