Effectiveness of Ropivacaine versus Levobupivacaine for Spinal Anaesthesia and Analgesia in Lower Limb Surgery
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 2
Abstract
Introduction: Newer local anaesthetic amides Ropivacaine and Levobupivacaine have gained popularity for spinal anaesthesia due to lower cardiotxicity and neurotoxicity. In this prospective, randomized double blind study we compare the effects of intrathecal isobaric ropivacaine 0.75% and levobupivacaine 0.5% in regards to the onset, regression, duration of sensory and motor blockade and also their hemodynamic stability, analgesic effect, and surgeon’s & patient’s satisfaction in term of surgical anaesthesia. Material and Methods: 68 patients of ASA1 to ASA3 physical status scheduled for lower limb surgery under spinal anaesthesia were recruited and randomized into Group L and Group R. Group L received 3ml of 0.5% Levobupivacaine and Group R received 3ml of 0.75% Ropivacaine intrathecally. Sensory & motor block onset, regression and hemodynamics were noted intraoperatively. Total duration of blockade and analgesia were noted postoperatively. Results: Group L had faster onset and longer duration of sensory and motor block with shorter motor regression time in comparison to Group R thus not hampering mobilization .Group L also had a longer time to first rescue analgesia and higher degree of patient’s and surgeon’s satisfaction in terms of surgical anaesthesia and were more hemodynamically stable in comparison to Group R. Conclusion: Both Ropivacaine and Levobupivacaine have desirable blocking property and can be used for lower limb surgery. Levobupivacaine provides more effective anaesthesia in term of onset, duration and longer period of post operative analgesia with lesser side effects and better patient’s and surgeon’s satisfaction in comparison to Ropivacaine.
Authors and Affiliations
Dr Alpa M Patel
Keywords
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