Effects of crude methanol extract of the fruit of Cucumis metuliferus (Cucurbitaceae) on some haematological parameters in cockerels
Journal Title: UNKNOWN - Year 2018, Vol 7, Issue 2
Abstract
The ripe fruits of C. metuliferus were collected in Vom village, Jos South Local Government Area, Plateau State, Nigeria. The fruits were washed and sliced using clean knives, and then air dried in the laboratory and pulverized. The dried powder was serially extracted using solvents of different polarities (n-hexane, chloroform, methanol and distilled water). The biochemical research involving animals was carried out according to the principles of Council for International Organizations for Medical Science (CIOMS) and the International Council for Laboratory Animal Science (ICLAS), 2012 and was approved by the Ethics Committee, Faculty of Veterinary Medicine, University of Maiduguri, Borno State, Nigeria. Twenty, 7-week old cockerels were used for this study. They were randomly divided into four groups of 5 chicken each (groups A, B, C and D). Cockerels in group D served as the untreated control and were given only feed and distilled water daily for a period of 28 days. The cockerels in groups A, B and C were treated daily orally with graded doses of the most active of the fruit extracts, that is crude methanol extract (CME), (200, 400 and 600 mgkg-1 respectively). Haematological effect of the prolonged administration of the extract was examined in cockerels. Birds treated with 200, 400 and 600 mg/kg of the extract exhibited significant (p<0.05) increase in PCV, Hb and RBC count on day 14 and 21 after treatment. There was a significant (p<0.05) decrease of MCV and MCH throughout the periods of experiment of the treated groups, while MCHC significantly (p<0.05) decrease after 7 days post-treatment.
Authors and Affiliations
Joy Gararawa Usman, Olufunke Adebola Sodipo, Ayi Vandi Kwaghe, Bitrus Wampana, Nendir John Haruna Umaru, Umar Kyari Sandabe
Keywords
Related Articles
- EP ID EP585075
- DOI -
- Views 92
- Downloads 0
Kidney disorders and management through herbs: A Review
Kidneys have a vital role in the normal physiology of humans. Worldwide chronic kidney disease has become a major cause for disability and in worst circumstances leads to death. Major renal disorders occur due to diabete...
Analgesic and anti-Inflammatory activity of Tradescantia fluminensis leaves extract
Objective: The present study sought to evaluate the anti-inflammatory and analgesic activities of ethanolic extract from Tradescantia fluminensis leaves. Methods: The crude leaf extract of T. fluminensis was investigated...
Medicinal plants with anti-inflammatory activity
Inflammation is part of the body's immune response. There can be four primary indicators of inflammation: pain, redness, heat or warmness and swelling. Plants have the ability to synthesize a wide verity of phytochemical...
Amelioration of histological changes and associated metabolic abnormalities by a combination of Morinda lucida and metformin in diabetic rats
This work investigates the ability of Morinda lucida and co-administration of Morinda lucida/metformin in the control of biochemical and histological changes in alloxan-induced diabetic rats. Alloxan diabetic rats were t...
Pharmacognosy and Phytochemical Evaluation of Hygrophila auriculata (Schumach.) Heine. Root
The genus Hygrophila auriculata (Schumach.) Heine belongs to family Acanthaceae found in India. Commonly known Kokilaksa, as in Sanskrit. Root and seeds used as tonic, for asthama and dysentery (Bhuktar, 2000). Decoction...