EFFECTS OF LYCOPENE COMPUND ON OXIDATIVE STRESS TO REDUCE THE RATE OF CARDIAC COMPLICATIONS IN TYPE – II DIABETES MELLITUS
Journal Title: Int J of Pharm Rev& Res - Year 2014, Vol 4, Issue 3
Abstract
The objective of the present study is to evaluate the beneficial effect of tomatoes, which are rich source of Lycopene, relatively a new carotenoid known to play an important role in human health and disease. In this study the levels of serum enzymes involved in antioxidant activities like Super Oxide Dismutase, Glutathione Peroxidase, Glutathione Reductase, Reduced Glutathione, in type-II diabetic group (n = 30) and control group (n = 30), and observed significantly lower levels of antioxidant enzymes in type-II diabetes when compared to control group (p<0.001). Short term supplementation with tomatoes (cooked) to diabetic group for a period of 21 days, showed a significant improvement in antioxidant enzyme levels suggesting the supplementation with tomato lycopene may serve as the best method of preventing the oxidative stress in diabetic patients
Authors and Affiliations
Ali Raza Memon1 , Hina Riaz2 , Keenjhar Rani2
Keywords
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