EFFECTS OF MULUNGU (ERYTHRINA MULUNGU) AND NRG® (HERBALIFE) IN THE BEHAVIORAL PROFILE AND WEIGHT OF WISTAR RATS
Journal Title: World Journal of Pharmaceutical and Medical Research - Year 2017, Vol 3, Issue 5
Abstract
Erythrina mulungu (EM) is a Southern Brazilian plant commonly used in folk medicine as sedative, hypnotic, hypotensive, analgesic and as anti-convulsivant. NRG® (HERBALIFE) is a commercial product that contains maltodextrin, black tea, guarana, and caffeine, and its use is to increase metabolism rate and caloric burns and thus helps to lose weight. The lifestyle of modern societies leads people to seek alternatives to weight loss and, on the other hand, lead to the need to consume products that reduce anxiety. For this reason, the aim of this study was to compare the effects of EM and NRG® on the behavior and nutritional status of Wistar rats. After approval by the Ethics Committee, thirty male Wistar rats were divided in G1 (Control group that received water and feed ad libitum), G2 (Group treated with Erythrina mulungu solution (1g of EM extract/200mL of water) and rat feed ad libitum, and G3 (Group treated with NRG® solution (1g of NRG® powder/200mL of water) and rat feed ad libitum). After forty days, animals performed the Elevated Plus Maze (EPM) to the evaluation of anxiety. Body weight was evaluated every 7 days. Our results showed no significant differences among the groups when performing the Elevated Plus Maze but G2 and G3 increased body weight at the end of the experimental protocol. Substances commonly used by the population for specific purposes does not always produce the expected results as they may not have the quality needed to present the effects shown in the literature. Our data show that the two products did not produce significantly different behavioral effects in the animals. In addition, substances that claim to reduce anxiety like EM or that are used as thermogenic should not increase weight gain in animals that received the same amount of food.
Authors and Affiliations
Dr. Sandra Maria Barbalho
Keywords
Related Articles
- EP ID EP654876
- DOI -
- Views 177
- Downloads 0
ROLE OF SERUM C-REACTIVE PROTEIN IN ANTIBIOTIC THERAPY IN NEONATAL SEPSIS
Objective: To evaluate the adequacy of serum C-reactive protein (CRP) in diagnosing neonatal sepsis and role of CRP in determining the duration of antibiotic treatment in neonatal sepsis. Methods: In this validation stud...
STUDY OF CLINICAL PRESENTATION, LABORATORY AND RADIOLOGICAL FINDINGS IN ACUTE APPENDICITIS AT A TERTIARY CARE UNIT
Background: Appendicitis is the inflammation of the appendix. It is a disease of the young, with 40% of cases occurring between the ages of 10 and 29 yrs. The present study involves diagnostic study of clinical, laborato...
PREVENTION OF PARENT TO CHILD TRANSMISSION: A RIMS REVIEW
Introduction: Prevention of parent-to-child transmission (PPTCT) services is an integral part of National AIDS Control Programme and their critical appraisal is necessary for improving quality care. This retrospective st...
RENAL CALCULUS - A REVIEW ARTICLE
Lactic acid bacteria, Lactobacillus plantarum and Lactobacillus pentosus, were isolated from the breast milk of six healthy breast feeding mothers using MRS agar media and API50CHL kit and the total Lactic Acid Bacteria...
L-ASPARAGINASE: ACTION, SOURCES, APPLICATION AND SIDE-EFFECTS
L-Asparaginase (L-asparagine aminohydrolase-EC3.5.1.1) commercial valuable enzyme hydrolyzes the amino acid L-asparagine in to aspartic acid and ammonia. L-Asparaginase is one of the worldwide used enzyme in clinical sec...