Effects of Petrol Fumes on Renal Function Parameters of Petrol Station Attendants in Sagamu, Nigeria
Journal Title: Journal of Clinical Medical Research - Year 2025, Vol 6, Issue 1
Abstract
Petroleum fuels contain many toxic chemical compounds and trace metals. Previous studies on the effects of exposure to petroleum fuels on the kidneys in occupationally exposed workers are contradictory. This was a cross-sectional study conducted on 60 participants, including 30 petrol station attendants who have been on the job for at least one year and 30 age and sex matched controls in Sagamu metropolis, Nigeria, that have never been occupationally exposed to petroleum fuels. Blood samples were taken from the participants for the analysis of routine kidney function parameters. The plasma concentrations of sodium, potassium, chloride, bicarbonate, urea and creatinine were determined. The estimated creatinine clearance was calculated using the Cock-croft Gault equation. Significantly (p < 0.05) higher plasma urea levels were found in the petrol station attendants when compared to their control counterparts and the levels of plasma sodium, chloride and the calculated creatinine clearance were significantly (p < 0.05) lesser in petrol station attendants than in the control group. The results of this study based on the period of exposure have not indicated any progression to renal disease as compared to the control group but however suggest a tendency towards azotaemia and subclinical, prepathologic effects on the kidneys.
Authors and Affiliations
Omoviye Onome Emmanuel1, Usiobeigbe Osahon Stanley2, Omolumen Lucky Eromosele2, Airhomwanbor Kingsley Osayande2, Obohwemu Kennedy Oberhiri3, Asibor Ernest4, Dongyeru Edmund5, Anukwe Chukwumelije N6,7, Ebaluegbeifoh Lucky Osemu8, Yakubu Bot Sunday9, Aliche Peace Chidi10, Babatope Stella Adesola11, Iyevhobu Kenneth Oshiokhayamhe12,13
Keywords
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- EP ID EP762318
- DOI https://doi.org/10.46889/JCMR.2025.6108
- Views 2
- Downloads 0
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