EFFECTS OF PSYCHOTROPICS ON NEUTROPHIL-LYMPHOCYTE RATIO IN PSYCHIATRIC PATIENTS
Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2019, Vol 12, Issue 6
Abstract
Objective: The objective of this study was to investigate whether psychotropic has any effect on neutrophils and lymphocyte ratio (NLR) in psychiatric patients. Methods: In this hospital-based prospective quasi-randomized follow-up study, we analyzed every 10 patients with newly diagnosed with depression, schizophrenia, and bipolar disorder for complete blood count before and after treatment with the selected psychotropic. Results: There was a significant increase in NLR of patients with depression after treatment with psychotropic (p=0.001), also in schizophrenia, there was a slight increase in NLR of patients after treatment with psychotropic (p=0.005), but in bipolar disorder, there was a significant decrease in NLR of patients after treatment with psychotropic (p=0.002). Conclusion: The present study confirmed that psychotropics have a statistically significant effect on the increase in NLR in patients with depression, a slight increase in patients with schizophrenia, and a decrease in patients with bipolar disorder. Further studies are needed for a better understanding of the mechanism of psychotropic drug effect on NLR.
Authors and Affiliations
RAJESH VENKATARAMAN , MUHAMMED RASHID , AKHILA G , SHIJO DANIEL , AMALATHOMAS
Keywords
Related Articles
- EP ID EP608985
- DOI -
- Views 143
- Downloads 0
A REVIEW ON THE SYNTHETIC METHODOLOGIES OF CHROMONES
Chromones group of compounds and their derivatives form the essential component of pharmacophores in many biologically active molecules. They exhibit a wide range of biological activities such as antibiotic, antitumor, a...
SIMULTANEOUS DETERMINATION OF DIPHENHYDRAMINE, EPHEDRINE, NOSCAPINE, AND GLYCEROL GLYCOLATE USING STABILITY-INDICATING HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY: APPLICATION TO NOSCOF TABLETS
Objective: Noscof tablet is a fixed dosage combination formulation having diphenhydramine (DH), ephedrine (ED), noscapine (NP), and glycerol glycolate (GG). A sensitive, selective, accurate, precise, and stability-indica...
PHARMACOGNOSTIC STUDIES ON FLOWERS OF DREGEA VOLUBILIS: EVALUATION FOR AUTHENTICATION AND STANDARDIZATION
Objective: The various parts of Dregea volubilis (Family: Apocynaceae), locally known as Jukti (Bengali), are commonly used in Indian system of medicine to treat various ailments such as inflammation, piles, leukoderma,...
NANOSTRUCTURE LIPID CARRIERS: A PROMISING TOOL FOR THE DRUG DELIVERY IN THE TREATMENT OF SKIN CANCERNANOSTRUCTURE LIPID CARRIERS: A PROMISING TOOL FOR THE DRUG DELIVERY IN THE TREATMENT OF SKIN CANCER
Skin cancer is the most common type of cancer having a very high rate of incidence, exceeding the sum of all other types of cancers. Current topical treatments for non-melanoma skin cancer and their precursor lesions, su...
DEVELOPMENT AND CHARACTERIZATION OF BIOCOMPATIBLE POLYHYDROXY BUTYRATE IMPREGNATED WITH HERBAL PLANTS AGAINST WOUND HEALING ACTIVITY ON IN VIVO ANIMAL MODEL
Objective: The current study is to evaluate the antimicrobial, antioxidant, anti-inflammatory, and in vitro cytotoxicity activities of polyhydroxybutyrate (PHB) and to develop the herbal impregnated PHB cast film for wou...