Effects of Some Selected Brands of Antifungal With and Without Specific Antifungal Activities on Microsporiumcanis and Epidermophytonfloccosum
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2018, Vol 13, Issue 3
Abstract
Effects of some selected brands of antifungal with and without specific antifungal activities on Microsporiumcanis and Epidermophytonfloccosumwas carried out to ascertain their potency. Punch hole diffusion method was used to determine the susceptibility of dermatophytes to different brands of topical antifungal with and without specific antifungal activities. Minimum Inhibitory Concentration and Minimum Fungicidal Concentration was determined to ascertain potency.EpidermophytonfloccosumandMicrosporum Canis were subjected to twelve brands of topical anti-fungal creams (Betrosil, Funbact-A, Fluzec-NM,3G, Miracute, Mycoten, Mycozoral, Nixoderm, Quadriclear, Skineal, Tribotan and Tydineal) and four other selected agents without specific antimicrobial functions namely close up toothpaste, dabur herbal toothpaste, hydraulic fluid and shea butter).There was statistically significant difference (P ˂ 0.05) between Quadriclear, Miracute, Tydineal, Betrosil, Mycoten, Funbact-A, Fluzec-NM and Tribotan and they were fungicidal. There was no significant difference (P ˃ 0.05) between Skineal, mycozoral, 3G and Nixoderm and they werefungistatic. Statistically there was significant difference (P ˂ 0.05) between Hydraulic fluids and other selected agents without specific antifungal activities. Hydraulic fluid showed fungicidal activity on the twodermatophytes tested Therefore antifungal creams should be used on dematophytes topically. Use of non-antifungal agents such as hydraulic fluid with antifungal properties should be prohibitedas this might constitute health hazard.
Authors and Affiliations
Gberikon, G. M, *Iwodi, C,, Awodi, F. E
Keywords
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- EP ID EP395414
- DOI 10.9790/3008-1303047276
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