Serum Thyroid Hormone Levels in Sudanese Patients with Liver Cirrhosis
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 6
Abstract
Background: There are clinical and laboratory associations between thyroid and liver diseases. Patients with chronic liver disease such as cirrhosis may have thyroiditis, hyperthyroidism, or hypothyroidism, because thyroid hormones (THs), particularly triiodothyronine (T3), are potent regulators of multiple physiological activities. The goal of the study is to assess the relationship and interconnection between thyroid hormones, and liver cirrhosis patients. Objectives: A case control study was conducted at Ibn Sena Specialist hospital in Khartoum state, Sudan, during the period of February - June 2016. Participants (N/80) were divided into two groups; patient group (N/40) between the ages of 20-80 years old diagnosed as cirrhosis patients based on their medical record and without any history of without any other chronic condition, controls known as healthy subjects group (N/40). Results: in comparison with the controls, patient withcirrhosis had significantly lower levels of T3Mean= [1.7685] ±SD (.52121),P=0.01, thancontrols [2.0220] ± (.31430), while TSH, [1.8993] ± (1.01434) vs. 1.8993±1.01434 for controls, P=0.556, andT4 [105.3340] ± (40.22112) vs.160.3480±224.51627 for controls=0.131)were in significantly changed. Conclusion: The current study revealed a significant decrease level of T3 and an in significant change in TSH and T4levels than control groups.
Authors and Affiliations
Hussein Awad Mousa, Husham O. Elzein2, NassrEldin M. A. Shrif, Amna O. M. Elzein3 *
Keywords
Related Articles
- EP ID EP386796
- DOI 10.9790/3008-1106041418
- Views 78
- Downloads 0
Evaluation of Anti-inflammatory and Antisickling Potentials of Archidium ohioense (Schimp. ex Mull) Extracts
The study investigated the possible anti-inflammatory and antisickling potential of a moss plant A. ohioense.The phytoconstituents of acetone, chloroform and ethylacetate extracts of the plant were analysed using standar...
Study of Peak Expiratory Flow Rate and Blood Oxygen Saturation in Female Beedi Rollers
Background: Beedi rolling is one of the largest small scale industries in India providing employment to millions of women having low socioeconomic status. They are constantly exposed to tobacco dust and its alkaloids whi...
Comparison of Cognitive Impairment in Type-2 Diabetic Patients Treated with Different Anti diabetic Drug Groups
Background and objective; Type 2 diabetes mellitus (T2DM) is a modern day epidemic. Chronic course of diabetes is detrimental to the cognitive functions Anti-diabetic drugs like insulin, oral-hypoglycemic agents (OHA) sl...
Removal of the Bad Effects of D-Galactosamine on Blood Lipids of Male Wistar Rats By Black and Green Tea Consumption
There is an increase in overall health awareness in Saudi Arabia due to a rising rate of diseases such as diabetes and heart diseases in addition to obesity. Thus, Saudi Ministry of Health initiates many programs to impr...
Ethanolic Extracts of Copaifera Multijuga Inhibits the Subcutaneous Growth of Ehrlich Carcionoma in Swiss Mice
Oil-resin of Copaifera multijuga Hayne is popularly used due to its anti-inflammatory properties. In this study, we evaluate the effects of the bark ethanolic extract on Ehrlich tumor cells. For extract preparation, bark...