Comparison of Cognitive Impairment in Type-2 Diabetic Patients Treated with Different Anti diabetic Drug Groups
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 5
Abstract
Background and objective; Type 2 diabetes mellitus (T2DM) is a modern day epidemic. Chronic course of diabetes is detrimental to the cognitive functions Anti-diabetic drugs like insulin, oral-hypoglycemic agents (OHA) slow the progression of dementia and their by improving the cognitive status. In this study we compared the cognitive status among type 2 diabetes mellitus patients treated with different anti-diabetic drugs. Methods; A prospective observational study is conducted in a group of 150 type 2 mellitus outpatient and inpatient attending diabetic clinic of medical college Calicut. The subjects are divided in to three groups, group-1 taking OHA, group-2 taking insulin and group-3 taking both insulin and OHA. We analyzed the cognitive impairment using MOCA questionnaire. Result; patients taking oral hypoglycemic agents have a greater MOCA pass percentage (46.2%) followed by patients taking insulin alone (40.9%) and the least pass percentage is for patients taking combination of insulin and oral anti-diabetic drugs (38.9%) but the statistical analysis shows no significant relation between the cognitive impairment and anti-diabetic drugs group as p value was found to be >0.05.
Authors and Affiliations
Arjun M, Sreejith K, Dr. Sajeeth Kumar K. G2
Keywords
Related Articles
- EP ID EP386643
- DOI 10.9790/3008-1105043947
- Views 93
- Downloads 0
Vegetative Growth, Yield and Some Characteristics of Onion (Allium Cepa L.) Genotypes As Influenced By Transplant Age in Eastern Regions of Hormozgan Province, Iran
In order to determine the best onion transplant age in Minab region of Hormozgan province, Iran, an experiment was performed as factorial arrangement in randomized complete block design with three replications in two suc...
Accounting and Finance Educationin Nigeria: Challengesand Changesfor Efficiency.
In this study, an attempt was made to reflect into the historical development of Accounting and Finance education in Nigeria. It examined the various challenges bedeviling the system and the need to refocus because it pr...
Morphometry of Cirrhinus reba (Hamilton) from Sukhna Lake, Chandigarh, India
For morphometric analysis of Cirrhinus reba (Ham.), 80 fish specimens were collected during the period from June 2012 to May 2014 from Sukhna Lake, Chandigarh. Out of all 24 morphometric characters studied, three charact...
Systematic Significance of Palisade Ratio In Pharmacognostic Applications
The palisade ratio is calculated for 117 taxa of tropical Acanthaceae. The mean palisade ratio values range from 1.45 to 25.0, the lowest and highest being observed in Pseuderanthemum reticulatum and Strobilanthes barbat...
Bacterial Isolates from Seafood in Scotland
Vibrio spp., Enterobacteriaceae representatives and Listeria monocytogenes were isolated from commercially prepared smoked and fresh Atlantic salmon, smoked and fresh haddock, live mussels and oysters. Isolates were iden...