Comparison of Cognitive Impairment in Type-2 Diabetic Patients Treated with Different Anti diabetic Drug Groups
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 5
Abstract
Background and objective; Type 2 diabetes mellitus (T2DM) is a modern day epidemic. Chronic course of diabetes is detrimental to the cognitive functions Anti-diabetic drugs like insulin, oral-hypoglycemic agents (OHA) slow the progression of dementia and their by improving the cognitive status. In this study we compared the cognitive status among type 2 diabetes mellitus patients treated with different anti-diabetic drugs. Methods; A prospective observational study is conducted in a group of 150 type 2 mellitus outpatient and inpatient attending diabetic clinic of medical college Calicut. The subjects are divided in to three groups, group-1 taking OHA, group-2 taking insulin and group-3 taking both insulin and OHA. We analyzed the cognitive impairment using MOCA questionnaire. Result; patients taking oral hypoglycemic agents have a greater MOCA pass percentage (46.2%) followed by patients taking insulin alone (40.9%) and the least pass percentage is for patients taking combination of insulin and oral anti-diabetic drugs (38.9%) but the statistical analysis shows no significant relation between the cognitive impairment and anti-diabetic drugs group as p value was found to be >0.05.
Authors and Affiliations
Arjun M, Sreejith K, Dr. Sajeeth Kumar K. G2
Keywords
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- EP ID EP386643
- DOI 10.9790/3008-1105043947
- Views 86
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