Effects of Soya Beans Supplements on Fertility in Male Wistar Rats
Journal Title: Macedonian Journal of Medical Sciences (MJMS) - Year 2011, Vol 4, Issue 1
Abstract
Background. Being a cheap source of protein and oil, soya beans (SB) has being important in peoples’ food and in animal’s feeds. However, some of its components pose infertility threats. This makes the decision for its consumption hard. Aim. To determine a safe level, the maximum harmless proportion of food that could be made up by SB is examined in this study. Material and Methods. Twenty-four adult male Wister rats, randomly divided into four groups (of 6 rats each), were used. Group A was the control and were fed growers mash pellets. Group B, C, and D rats were fed derivatives of growers mash containing 8.33 %, 16.67 %, and 25.00 % SB . All treatments were for twelve weeks. Relative epididymal weight, sperm count, morphology, motility, serum testosterone level were determined. The groups were compared using independent sample t-test. Results. The results showed that unlike in rats fed with mash containing large amount of SB, fertility abnormalities were almost entirely absent in the rats fed with the least proportion of soya beans. Therefore, the potential antifertility effect of soya beans used in feeds/foods might be averted if the proportion of the soya used could be lower than 5g per 60g of feed/food. Conclusion. The potential antifertility effect of soya beans used in feeds/foods could be averted if the proportion of the used soya would always be lower than 8.33% of feed/food. Further research for the verification of this study, and for the derivation of a more precise safe level of soya beans are encouraged.
Authors and Affiliations
Olusola Atilade Adeeyo| Department of Anatomy, Faculty of Basic Medical Sciences, College of Medicine, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria, Emmanuel Oluwatobi Salawu| Department of Physiology, Faculty of Basic Medical Sciences, College of Medicine, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria, Ibidun Julian Ola| Department of Anatomy, Faculty of Basic Medical Sciences, College of Medicine, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria, Waheed Adeoye Saka| Department of Physiology, Faculty of Basic Medical Sciences, College of Medicine, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria, Gbadebo Emmanuel Adeleke| Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria, Olasupo Stephen Adeniyi| Department of Physiology, College of Health Sciences, Benue State University, Makurdi, Benue State, Nigeria
Synovial Sarcoma of the Liver – A Case Report
We report a case of synovial sarcoma of liver in a 44 year old man, presented as a tumor mass in left hepatic lobe. The patient was admitted at the hospital with clinical symptoms of acute abdomen and severe pain in th...
Liver Carbohydrate Metabolism in Rats in the Period of Recovery after Acute Heat Stress
In the present work we have estimated the effect of acute heat stress (1 hour to 41±0,5°C) and the different period of recovery at room temperature after the heat stress (0, 30 minutes, 1, 6, 12, 24, 48 and 96 hours)...
Telomerase Activity and MDS/EVI Gene Fusion in Myelodysplastic Syndrome. Correlation to the Immunohistochemical Expression of Ki-67, Bcl-2 and p53 in Bone Marrow Biopsy Samples
Background. Myelodysplastic syndrome (MDS) as a complex disorder comprised of 7 entities may arise as a primary disorder, or in a setting of an underlying disease, or as therapy related (secondary MDS). Some cases show...
Aberrant Expression of Polycystin-1 in Renal Cell Tumors
Polycystin-1 (PC1) is a cellular transmembrane protein coded by the polycystic kidney disease (PKD1) gene, prevalently expressed in developing/mature kidney and in autosomal polycystic kidney disease (ADPKD). Limited d...
Extended-Spectrum Beta-Lactamase-Producing E. Coli and Klebsiella Pneumoniae in Children at University Pediatric Clinic in Skopje
Aim. The objectives of this study were to determine the prevalence and antibiotic susceptibility patterns of extended-spectrum β-lactamases (ESBL)-producing Escherichia coli and Klebsiella pneumoniae. Material and me...