Efficacy of Dexmedetomidine Compared to Clonidine added to Ropivacaine in Supraclavicular Nerve Blocks: A Prospective, Randomized, Double Blind Study
Journal Title: International Journal of Medical and Health Sciences - Year 2014, Vol 3, Issue 2
Abstract
Background: The supraclavicular brachial plexus blocks are one of the most commonly performed upper limb brachial plexus blocks. These blocks not only provides very good analgesia intraoperatively but also reduces incidence of complications like hypotension, bradycardia, delayed recovery from anaesthesia and also provides very good pain relief post operatively. Alpha-2 adrenergic agonists have become popular to prolong the duration of anaesthesia. In our study we have added dexmedetomidine and clonidine with ropivacaine 0.5% instead of bupivacaine since it is more cardio stable. Aims: The present study was aimed to test the hypothesis that dexmedetomidine produces a better analgesia, motor block and post operative analgesia when added as an adjuvant to ropivacaine 0.5% in supraclavicular brachial plexus block compared with clonidine. Material and Methods: One hundred patients, scheduled for various elective orthopedic surgeries on the upper limb belonging to ASA (American society of anaesthesiologists) class I and II were assigned randomly into two groups. Group RC received ropivacaine 0.5% (29 cc) + clonidine 1 μg/kg. Group RD received ropivacaine 0.5% (29 cc) + dexmedetomidine 1 μg/kg. Onset and recovery time of sensory and motor block, duration of analgesia and quality of block were studied in both the groups. Results: Dexmedetomidine prolongs the duration of sensory and motor block and enhances the quality of block as compared with clonidine when used as an adjuvant to ropivacaine in peripheral nerve block. Conclusion: Dexmedetomidine when added to ropivacaine for brachial plexus block is a better adjuvant compared to clonidine.
Authors and Affiliations
Harshavardhana H S
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