EFFICACY OF PRE-EMPTIVE ETORICOXIB IN PATIENTS UNDERGOING HERNIOPLASTY UNDER GENERAL ANAESTHESIA- A PROSPECTIVE RANDOMISED-CONTROLLED TRIAL
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 13
Abstract
BACKGROUND Obtaining adequate analgesia in the perioperative period is an enormous task. Studies show that etoricoxib, a selective COX-2 inhibitor given pre-emptively reduces the pain and thereby enhances recovery. The aim of the study is to evaluate the effect of pre-emptive etoricoxib in reducing intraoperative requirements of anaesthetic agents, decreasing postoperative pain and improving functional outcome in patients undergoing inguinal hernioplasty. MATERIALS AND METHODS Two groups, each of thirty patients were formed- Group S and Group C. Group S received a single dose of etoricoxib two hours prior to anaesthesia, while Group C received a placebo. Sevoflurane used during the intraoperative period was calculated. The patient’s pain, sleep and body language in the postoperative period was noted. The rescue analgesics were recorded. Statistical Analysis- The data was analysed using Mann-Whitney U test, Wilcoxon test, independent two sample t-test, Pearson Chi-square test and Fischer’s exact test. Settings and Design- The study was performed in the Department of Anaesthesia in Jubilee Mission Medical College and Regional Institute, Thrissur, from January 2015 to March 2016. This was a prospective study. RESULTS Age, gender and duration of surgery were comparable in both groups. The amount of sevoflurane consumed was less in group S. The postoperative pain was also less in group S at all the time points. Patients in group S demanded less rescue analgesics. 83.3% of the patients in group S had good sleep versus 26.7% in the group C. Up to 93.3% of the patients in group S had a relaxed body language versus 36.7% in group C. No adverse effects were noted. CONCLUSION Pre-emptive etoricoxib is thus a safe, simple and cost-effective therapy in reducing the intraoperative anaesthetic and postoperative analgesic requirements.
Authors and Affiliations
Vigil Peter, Peter Alapatt, Davies C. V
Keywords
Related Articles
- EP ID EP214113
- DOI 10.18410/jebmh/2017/143
- Views 131
- Downloads 0
CLINICO-HAEMATOLOGICAL STUDY OF PANCYTOPENIA IN A TERTIARY CARE CENTRE
BACKGROUND Pancytopenia is one of the pathological manifestation resulting from various underlying disease processes affecting the bone marrow. Hence, bone marrow examination is the diagnostic tool to detect the underlyi...
ANESTHETIC MANAGEMENT OF ATONIC POST-PARTUM HEMORRHAGE WITH HEMORRHAGIC SHOCK AND IMPENDING CARDIAC ARREST FOR EMERGENCY PERIPARTUM HYSTERECTOMY
Post-partum hemorrhagic complication is a critical situation for an anesthesiologist, which requires timely and skillful anesthetic management. A massive post-partum bleeding leading to severe hypovolemic shock may resul...
SELECTIVE EARLY SUTURE REMOVAL IMPROVES VISUAL ACUITY AND REDUCES ASTIGMATISM IN TRAUMATIC CORNEAL REPAIRS
Traumatic corneal injuries are the leading causes of blindness in young adults and frequently occur during occupational activities. Corneal astigmatism after post traumatic corneal wound repair is the most common complic...
MYCOLOGICAL STUDY OF ASPERGILLUS INFECTIONS IN KERATOMYCOSIS
In recent years, fungi have been emerging more commonly as infectious agents in patients of tertiary care centers. AIM: The present study was undertaken to find out the prevalence of aspergillus infection causing keratom...
DIAGNOSIS OF MDR TUBERCULOSIS AT A TERTIARY CARE CENTRE WITH CBNAAT TECHNOLOGY- A TWO YEAR STUDY
BACKGROUND Tuberculosis is a chronic multi system granulomatous disease with a predilection for the respiratory system. Traditional diagnostic protocols include history, chest x-ray and sputum collection and staining for...