Efficacy of Tocilizumab vs. NSAIDs in the Treatment of Juvenile Rheumatoid Arthritis

Abstract

Tocilizumab is a humanized monoclonal antibody that binds to IL-6 receptors, both the soluble receptor (sIL-6R) and the one located in the cell membrane. In this way it blocks the molecular complex of the receptor and prevents cytokine signaling. It is a drug which has recently been approved by the FDA, several studies recently carried out at international level (USA, Japan, Europe) have demonstrated the great efficacy of tocilizumab in the treatment of juvenile rheumatoid arthritis.

Authors and Affiliations

Daniela I. Sánchez, Paola L. Padilla, Felix Osuna Gutierrez, Giancarlo T. Ornelasa, Flavio Humberto Ávalos

Keywords

Related Articles

Emotional Burn out Syndrome: The Essence of the Concept and the History of its Study

Occupational stress is a multidimensional phenomenon that manifests itself in physiological and psychological reactions to a difficult work situation. The development of stress factors is possible even in progressive, we...

A Clinicopathological Study of Mucocutaneous Lesions in Correlation with CD4 Counts in HIV Seropositive Cases at a Tertiary Care Centre in South India

Background: Mucocutaneous lesions are one of the first clinical presentations of immunosuppression in Human Immunodeficiency Virus (HIV) seropositive patients that manifest at different stages of the infection th...

Importance of Reconstructive Breast Surgery after Mastectomy

Reconstructive breast surgery can significantly improve patients' quality of life after a mastectomy, which can have a positive impact on their psychological well-being. Patients who undergo breast reconstructive surgery...

Melasma, A Guide of Management

Melasma management is frequently difficult, with many examples of inadequate remission and repeated relapses. Depending on the patient's features and clinical presentation, a multimodal treatment involving ph...

A Rare Case : Traumatic Posterior Hip Dislocation Associated with Anterior Column and Incomplete Posterior Column Acetabular Fracture

Introduction:The hip is among the most solid joints within the human body that took a lot of force to dislocate it. Hip dislocation is frequently associated with acetabulum fracture. Although traumatic posteri...

Download PDF file
  • EP ID EP713747
  • DOI 10.47191/ijmscrs/v2-i4-02
  • Views 44
  • Downloads 0

How To Cite

Daniela I. Sánchez, Paola L. Padilla, Felix Osuna Gutierrez, Giancarlo T. Ornelasa, Flavio Humberto Ávalos (2022). Efficacy of Tocilizumab vs. NSAIDs in the Treatment of Juvenile Rheumatoid Arthritis. International Journal Of Medical Science And Clinical Research Studies, 2(04), -. https://europub.co.uk/articles/-A-713747