Efficiency of Single Dose Antibiotic Prophylaxis in Inguinal Hernioplasty
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 7
Abstract
Introduction and objectives: Surgical site infection (SSI) is the most frequent complication in inguinal hernioplasty.SSI is related with an increase in length of stay and costs and a decrease in quality of life. Use of antibiotics in Lichtenstein’s hernia repair is still debatable in a rural set up. Another subject in rural setup that must be addressed in antibiotic prophylaxis is cost-effectiveness. In these cases, the costs of antibiotic administration must be carefully evaluated against the potentials benefits. Materials and Methods: The study was conducted out between December 2014 to October 2016 on 60 patients. The patients were assigned alternately into 2 groups. Cases in Group A received single dose of pre-operative antibiotic 30 minutes before surgery and cases in group B received multiple doses perioperatively. The patients were then monitored post operatively from the second day onwards for SSI. The data was collected and statistics done using the Chi square/Fischer exact test to look for significant difference in the rate off SSIs in both the groups and also to find out if it was cost effective. Results and Inferences: Incidence of SSI in group A was 3.33% (1 in 30). Incidence of SSI in group B was 6.6%( 2 in 30).Incidence of SSI though higher in group B than group A was not statistically significant when Fischer exact test was applied. The cost of antibiotic per patient in group A was Rs.32 while that in group B was between a minimum of Rs.192 in patients without SSI to a maximum of Rs.340 with SSI. The difference in cost of antibiotic in both groups was statistically significant. Conclusion: Single dose antibiotic prophylaxis was therapeutically efficient as well as cost effective in comparison with multiple doses of perioperative antibiotics usage for the prevention of surgical site infection in uncomplicated elective cases of Lichtenstein’s hernioplasty.
Authors and Affiliations
Pavan BK
Histopathological Spectrum of Uterine and Cervical Lesions in Hysterectomy Specimens
Background: For centuries, the female reproductive system has been affected by various abnormalities and diseases and hence has been the subject of interest and the basis for the gynaecological practice. The uterus being...
A Case Report on Acquired Pure Red Cell Aplasia in a Patient of Rheumatoid Arthritis
Pure red cell aplasia (PRCA) is a clinical syndrome defined by the absence of mature erythroid precursors in another wise normocellular bone marrow. PRCA is considered to be an extra articular manifestation of rheumatoid...
Apert’s Syndrome - A Case Report and Review of Literature
Apert's syndrome makes up approximately 4% of all cases of craniosynostosis. The incidence is reported to be 1/160,000 live births [1]. Radiology has an important role in the evaluation, management and follow up of Apert...
Study of the Baseline Widal Titres among Healthy Population in a Tertiary Care Hospital in Central India
Background: In developing countries like India, Enteric fever is endemic. Widal agglutination test is used for its diagnosis. In a single serum sample the only test frequently relied upon for laboratory diagnosis is Wida...
Comparison of Fentanyl and Dexmedetomidine added to low dose Bupivacaine Heavy for Spinal Anaesthesia in Lower Abdominal Surgeries
Spinal anaesthesia is the most commonly used technique for below umbilical surgeries. It is economical, easy to administer and relatively safer. It is important to limit the block level for minimizing hemodynamic changes...