Electrocardiographic Alterations in Patients with Common Variable Immune Deficiency
Journal Title: Istanbul Medical Journal - Year 2020, Vol 21, Issue 2
Abstract
Introduction: Common variable immunodeficiency (CVID) is the most heterogeneous group among the antibody deficiency syndromes, but its effects on the cardiovascular system have not yet been clearly identified. Here, we aimed to investigate the arrhythmogenic effects of this disease with electrocardiography. Methods: The study included 30 CVID patients and 30 control subjects matched for age and comorbidities. Electrocardiographic and echocardiographic values of all participants were recorded. QRS, QT, Tp-e were measured manually. QTc was calculated using Bazett’s formula. Then, Tp-e/QT, Tp-e/QTc, QT/QRS, and QTc/QRS ratios were calculated and compared between the groups. Results: PR interval and P-wave dispersion were found to be higher in the CVID group. In addition, the QT interval and corrected QT interval, T peak-to-end interval were higher in the CVID arm, and the index of cardiac electrophysiological balance value obtained with the QT/QRS ratio was also higher in the CVID group. The number of patients with P terminal force was also higher in the CVID group. Conclusion: As a result of this study, it was found that CVID patients have a higher incidence of developing arrhythmia than normal healthy individuals.
Authors and Affiliations
Yakup Alsancak, Fatih Çölkesen
Keywords
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- EP ID EP685069
- DOI 10.4274/imj.galenos.2020.47855
- Views 113
- Downloads 0
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