ELISA versus Rapid test kits for screening of HIV and Hepatitis B and Hepatitis C among Blood donors in a tertiary care hospital
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 3
Abstract
Abstract: HIV, HBV and HCV pose a major public health problem through the world. Detection of infection markers for these agents is a major challenge in a resource poor setting. A blood transfusion service is a vital part of modern health care system. So it is mandatory to test each and every unit of donor blood for antibodies to HIV1 and 2, Hepatitis C, Hepatitis B surface agent, Syphilis and Malarial parasite. In our study 11879 donor samples were tested for HIV 1 and 2, HBsAg and HCV by ELISA and samples found reactive were again tested by rapid test kits Out of these, 326 samples were reactive for HCV by ELISA but only 237 samples were reactive by RDT. On testing for HBsAg, 127 samples were reactive by ELISA but only 102 were reactive in Rapid tests and for HIV 43 samples were reactive by ELISA but only 18 samples were reactive by RDT. Keywords:Transfusion Transmitted Infections (TTI), HIV 1 and 2, Hepatitis B, Hepatitis C, Rapid Detection Tests (RDT)
Authors and Affiliations
Neetu Kukar, Ravinder Garg, R. N. Maharishi, Neha Syal, Harkiran Arora, Anjali Handa
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