EMPLOYMENT OF PHOTOLYTICAL AND PHOTOCATALYTICAL METHODOLOGIES FOR REMOVAL OF CEPHALEXIN IN AQUEOUS SOLUTION
Journal Title: Periódico Tchê Química - Year 2017, Vol 14, Issue 27
Abstract
This study aimed to determine the best conditions for the photodegradation of the antibiotic cephalexin (CPX) in aqueous solution employing UV light, hydrogen peroxide (H2O2), titanium dioxide (TiO2) as catalyst at different pH values. The experiments were followed by spectrophotometry in the UV-VIS region observing the band at 262 nm (λmax). For the photocatalycal tests using homogeneous and heterogeneous catalysts, the parameters were organized in an experimental design 23 in order to observe the influence of each one, as well as the interaction between them at the different pHs studied. The results of the experiments were assessed by means of statistical software, been performing analyses of effects, interactions, response surface and analysis of variance (ANOVA). For the kinetic analysis of the results graphs of ln(A0/A) vs. time were plotted. From the analysis of the results, it was observed that the best conditions found for the photodegradation process were [H2O2] = 1000 mg L-1 and [TiO2] = 50 mg L-1 at pH 4. The kinetic constant of the photocatalysis employing [H2O2] = 1500 mg L-1 at pH 4 was 3.4 times higher than that determined for the photolytical process at pH 4 (k = 10x10-4 min-1). It was possible to verify that the parameters pH, H2O2, as well as the interaction between the parameters H2O2 and TiO2 are significant for the process, and that the best photocatalycal conditions were at pH 4, TiO2 [50 mg L-1] and H2O2 [1000 mg L-1]. In the assay of antimicrobial activity against five bacterial strains it was observed that only two strains, E. coli and A. hydrophila, did not show sensitivity to the photochemically treated drug, showing that in these cases the drug had its antimicrobial activity decreased.
Authors and Affiliations
Mauricio Ferreira ROSA
Keywords
Related Articles
- EP ID EP252198
- DOI -
- Views 204
- Downloads 0
BIOTECHNOLOGICAL APPROACHES IN PROCESSING OF SECONDARY RAW MATERIALS OF MEAT INDUSTRY
The radical change in the quality of the processed meat raw materials, which does not meet the standards, calls for the necessity to apply biotechnology methods in order to improve the quality and obtain high nutritional...
SPATIAL EVALUATION OF THE WATER QUALITY FROM THE VELHAS RIVER CHANNEL, IN THE STATE OF MINAS GERAIS
This study presents an evaluation of the water quality variability of 19 monitoring stations located in the channel of the Velhas river, using multivariate statistical techniques - Cluster Analysis (CA) and Principal Com...
INTERNAL AND EXTERNAL INSPECTION OF 3D GEOLOGICAL MODEL CONSTRUCTION QUALITY
The relevance of this paper is justified by the fact that the authors turn their attention to the problem of building geological models, which are constructed in conditions of an uneven observation grid (drilled wells),...
COSMETIC PRODUCTION FROM GLYCERINE THE BIODIESEL
The present study aims to produce a cosmetic emulsion containing the co-product glycerine, generated in the production of biodiesel by the transesterification of canola oil. The first part of the work consisted in the pr...
PERFORMANCE CALCULATION OF SOLAR WATER HEATING UNIT AT A PETROL FILLING STATION
Alternative resources of energy supply are implemented more often. Due to the renewability and inexhaustibility of this energy source. This paper deals with the performance of a solar water heating unit. By using theory...