Encouraging Submission of Studies Seeing Stem Cell Biology in the Light of Physical Energies and Nanoscale Approaches: Towards a Regenerative Medicine without the Needs for Stem Cell Transplantation
Journal Title: NanoWorld Journal - Year 2016, Vol 2, Issue 2
Abstract
Compelling evidence demonstrate that our cells are able to generate electromagnetic signals [1-5] and mechanical oscillations [6-9], affording essential modulation of cell polarity. At the level of somatic cells and tissue resident stem cells cell polarity results from, and acts on the modulation of cellular ion fluxes, electric fields, and microtubular dynamics of the cytoskeleton and nucleoskeleton. Cell polarity is crucial in the physiological modulation of stem cell differentiation and aging, as shown by the fact that altered cell polarization invariantly associates with disease, pathological aging and cancer [10-13]. To this end, the cytoskeletal and nucleoskeletal microtubular network form a major dynamic environment to establish and preserve cell polarity.
Authors and Affiliations
Carlo Ventura
Keywords
Related Articles
- EP ID EP223421
- DOI 10.17756/nwj.2016-024
- Views 68
- Downloads 0
Nanotechnology Advances in Drug Delivery
Drug delivery emerged as a discipline to solve problems associated with the majority of the current drugs, such as poor water solubility, poor physical stability, poor absorption and side effects. Large pharmaceutical co...
Stability and Radiation Damage of Protein Crystals as Studied by Means of Molecular Dynamics and Monte Carlo Simulation
Molecular Dynamics (MD) and Monte Carlo (MC) simulations of crystals can help in interpretation of experimental X-ray crystallography data. Particularly, they can be useful for understanding how various crystallization t...
Cancer Stem Cells: Foe or Reprogrammable Cells for Efficient Cancer Therapy?
Embryonic development and carcinogenesis share many molecular pathways and regulatory molecules. While the induction of a pluripotent state involves a significant oncogenic risk, as in induced pluripotent stem cells (iPS...
Ethanol Based Vesicular Carriers in Transdermal Drug Delivery: Nanoethosomes and Transethosomes in Focus
Transdermal route is one of the attractive routes for drug delivery due to its easy accessibility. Effective delivery of bioactive molecules through skin is however, still a challenge. The development of vesicular formul...
Proceedings of the First NanoWorld Conference in Boston (NWC-2016). Part II: Plenary Symposia
Regimen-related toxicities are common, often painful, disruptive and dose-limiting complications of many forms of chemo- and radiation therapy used for the treatment of cancer. In addition to their symptomatic and physio...