Epidemiological Analysis of [i]Mycobacterium tuberculosis[/i] Strains Isolated from Patients of Small Communities Living in the South-East of Poland
Journal Title: Polish Journal of Microbiology - Year 2015, Vol 64, Issue 3
Abstract
The diversity of [i]Mycobacterium tuberculosis[/i] clinical isolates, collected from a single hospital, was analyzed by ligation-mediated PCR techniques: FLiP and FLAP, and hybridization technique, IS[i]6110[/i]-RFLP. Isolated strains were divided in terms of location (3 towns of Podkarpackie voivodeship differing in population size) and relationship (8 members of 4 families, each represented by 2 patients). Within each family identical DNA profiles, as well as drug resistance patterns were identified indicating a great chance of transmission of strains within the same family. The identical, or very similar patterns were also shared by strains isolated from unrelated patients living in a very small town (1 200 inhabitants) or hospitalized in the same place and time.
Authors and Affiliations
Anna Zaczek, Iwona Szwaja, Monika Skiba, Czeslaw Puchalski, Karolina Lewandowska, Jaroslaw Dziadek
Keywords
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