Epidemiological and clinical profile of Japanese Encephalitis in Bengdubi garrison in West Bengal
Journal Title: IP International Journal of Medical Microbiology and Tropical Diseases - Year 2017, Vol 3, Issue 1
Abstract
Introduction: Japanese encephalitis (JE) is viral encephalitis that causes high morbidity and mortality and is endemic in large parts of West Bengal. Subclinical infections greatly outnumber overt cases of JE. The objective of this study was to detect cases of inapparent infections and the disease burden of JE in Bendubi garrison considered to be ‘endemic’ for JE. Methods: JE disease burden was evaluated by detection of anti-JEV IgM in serum and cerebrospinal fluid (CSF) in 510 cases of acute encephalitis syndrome (AES) reporting to the base hospital in Bengdubi while inapparent infections were evaluated by detection of serum anti-JE IgG antibodies in a matched sample of 511 individuals. Results: Fourteen (2.7%) of the 510 symptomatic cases that had presented to the hospital with fever or/and symptoms of acute encephalitis, tested positive for JEV infection. In the asymptomatic cohort, 429 out of 511 (83.9%) tested positive for the IgG antibody to JEV, giving an apparent: inapparent ratio of 1: 31. Conclusion: The overall incidence of JE cases was lower than that reported from other ‘endemic’ regions of West Bengal. Residents of the area developed IgG antibodies and hence longterm immunity against JE, probably as a result of repeated subclinical infections. Anti-mosquito measures, JE vaccination and environmental modifications can break the transmission cycle and eventually eradicate JE completely.
Authors and Affiliations
Aneeta Jassar, S. Srinivasa
Keywords
Related Articles
- EP ID EP301305
- DOI 10.18231/2455-6807.2017.0001
- Views 106
- Downloads 0
Detection of Siderophore production in Uropathogenic Escherichia.coli in patients with Type 2 Diabetes Mellitus
Introduction: Infection of the urinary tract is a common observation in patients with type 2 diabetes mellitus. UTI can be a severe complication in diabetic patients. The aim of this study was to determine siderophore pr...
Seroprevalence of Chikungunya virus infection in Ballari and nearby districts of Karnataka
Background and Objective: Chikungunya virus (CHIKV) is an arthropod-borne virus, causes fever and nonspecific clinical manifestations similar to malaria and other bacterial infections, it is not routinely tested at the h...
Resistant Genes blaCTX-M, blaTEM and blaSHV encoding ESBL in surgical site infection causing Escherichia coli and Klebsiella pneumoniae- A report from a tertiary care hospital
Introduction Surgical site Infections SSI rank third among hospital acquired infections worldwide According to the WHO report of 2016 the global burden of SSI ranges from 25 to 415 ESBL producing Ecoli and Klebsiella pne...
Evidence of potential threat of microbial drug resistance to commonly used antimicrobials in cases of active tubotympanic CSOM from Raipur, Chhattisgarh, India
Background: To identify the causative aerobic microbial pathogens of active tubotympanic (TT) type Chronic Suppurative Otitis Media (CSOM) and their antimicrobial susceptibility pattern. Method: A total of 248 clinically...
Prevalence of Nasal carriage of coagulase negative staphylococci and its antimicrobial susceptibility among ICU health care workers at a tertiary care hospital of Barabanki, UP
Introduction Health care workers HCW including medical as well as paramedical workers are a potential source of carrier of infection for the patients admitted in different intensive care units ICU The anterior nares are...