EPIDEMIOLOGICAL AND CLINICOPATHOLOGICAL MORPHOLOGY OF PATIENTS WITH HAEMOLYTIC ANAEMIA IN A TERTIARY CARE CENTER OF NORTH KERALA
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 45
Abstract
BACKGROUND Haemolytic anaemia’s are characterised by increased RBC destruction and evidence of accelerated erythropoiesis. Haemolysis due to intrinsic RBC disorders, i.e. the inherited haemolytic anaemias are more common. Most of these anaemias are easily recognisable under the light microscope. MATERIALS AND METHODS To study the clinical and morphological profile of different types of haemolytic anaemia due to RBC defects in patients admitted in a tertiary care hospital of North Kerala, India. RESULTS A cross-sectional study was carried out among 217 patients of haemolytic anaemia admitted in a tertiary care hospital over a period of five years from January 2012 to December 2016. The data on sociodemographic profile, relevant clinical history and clinical examination were collected in predesigned and pretested standard proforma and morphological parameters were assessed by using standard guidelines. CONCLUSION Sickle cell anaemia was found to be the most common of haemolytic anaemias reported in the hospital. HbE and HbD are extremely rare entities with only a single case report each. A single case of Paroxysmal Nocturnal Haemoglobinuria (PNH) was reported, this was included as it is an intrinsic RBC disorder.
Authors and Affiliations
Sheela Thomas, Rajan G, Chaganty Saikiranreddy, Shima Shima
TRAUMATIC GASTROPLEURAL FISTULA COMPLICATED BY EMPYEMA AND PNEUMOTHORAX
We herein report a case of traumatic gastropleural fistula complicated by empyema and pneumothorax which is a rare entity. A 22 year old male was admitted with alleged history of stab injury to left lower chest. Patient...
NOT ALL FOREIGN BODIES OF UPPER DIGESTIVE TRACT ARE ACCIDENTAL
To give the message that a sharp foreign body in the upper gastrointestinal tract in a female child is to be seen with caution as it could be a case of infanticidal attempt. CASE REPORT: A two and half month old baby pre...
RELATIONSHIP OF PROINFLAMMATORY CYTOKINES WITH MICROALBUMINURIA IN PATIENTS OF TYPE 2 DIABETES MELLITUS- IMPLICATIONS IN THE PATHOGENESIS OF DIABETIC NEPHROPATHY
BACKGROUND Type 2 diabetes mellitus is frequently associated with an increased inflammatory state. However, the relationship between of low grade inflammation and diabetic nephropathy still remains unclear with conflicti...
OUTCOME OF PERITROCHANTERIC FRACTURES TREATED WITH PROXIMAL FEMORAL NAIL VERSES DYNAMIC COMPRESSION SCREW
: The objective of this study is to compare the results of proximal femoral nail intramedullary fixation device verses dynamic compression screw with extramedullary device in the treatment of peritrochanteric fractures....
EFFICACY OF LAPAROSCOPIC OVARIAN WEDGE RESECTION IN RESISTANT POLYCYSTIC OVARIAN SYNDROME
BACKGROUND Poly Cystic Ovarian Syndrome (PCOS) is the most frequently encountered endocrinopathy in women, occurring in 4-7% of population. Many treatment options have been described including surgical methods. Wedge res...