EPIDEMIOLOGICAL AND CLINICOPATHOLOGICAL MORPHOLOGY OF PATIENTS WITH HAEMOLYTIC ANAEMIA IN A TERTIARY CARE CENTER OF NORTH KERALA
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 45
Abstract
BACKGROUND Haemolytic anaemia’s are characterised by increased RBC destruction and evidence of accelerated erythropoiesis. Haemolysis due to intrinsic RBC disorders, i.e. the inherited haemolytic anaemias are more common. Most of these anaemias are easily recognisable under the light microscope. MATERIALS AND METHODS To study the clinical and morphological profile of different types of haemolytic anaemia due to RBC defects in patients admitted in a tertiary care hospital of North Kerala, India. RESULTS A cross-sectional study was carried out among 217 patients of haemolytic anaemia admitted in a tertiary care hospital over a period of five years from January 2012 to December 2016. The data on sociodemographic profile, relevant clinical history and clinical examination were collected in predesigned and pretested standard proforma and morphological parameters were assessed by using standard guidelines. CONCLUSION Sickle cell anaemia was found to be the most common of haemolytic anaemias reported in the hospital. HbE and HbD are extremely rare entities with only a single case report each. A single case of Paroxysmal Nocturnal Haemoglobinuria (PNH) was reported, this was included as it is an intrinsic RBC disorder.
Authors and Affiliations
Sheela Thomas, Rajan G, Chaganty Saikiranreddy, Shima Shima
Keywords
Related Articles
- EP ID EP219995
- DOI 10.18410/jebmh/2017/547
- Views 74
- Downloads 0
ESTIMATION OF SERUM URIC ACID LEVELS IN NORMAL PREDIABETIC AND DIABETIC PERSON
BACKGROUND Raised serum uric acid has been associated with a lot of diseases like hypertension, cardiovascular diseases, chronic kidney disease, peripheral vascular diseases and metabolic disorders. But, the association...
EFFICACY OF PREGABALIN IN IMMEDIATE POST-OPERATIVE PAIN CONTROL
Ant nociceptive treatment started before surgery is more effective in reducing postoperative pain than if started in early postoperative period. Pregabalin has demonstrated efficacy in clinical trials as pre-emptive anal...
TO ASSESS THE PROPORTION AND SEVERITY OF DRY EYE FOLLOWING CLEAR CORNEA PHACOEMULSIFICATION SURGERY
BACKGROUND Dry eye is a multifactorial disease of the ocular surface characterized by a loss of homeostasis of the tear film. Corneal nerves are important in the self-regulation of a tear since they provide the sensation...
DOPPLER ASSESSMENT IN PREGNANCY-INDUCED HYPERTENSION AND USEFULNESS OF DOPPLER IN PREDICTING FOETAL OUTCOME
BACKGROUND Normal foetal growth and development depends on adequate perfusion of the intervillous space through the maternal spiral arterioles. Reduced perfusion is associated with asymmetrical retardation of the foetal...
COMPARING THE SAFETY AND EFFICACY OF ROSUVASTATIN AND ATORVASTATIN IN PATIENTS WITH CORONARY HEART DISEASES
BACKGROUND Heart disease is the leading cause of death in men and women in India and lowering LDL-C levels has become a cornerstone of heart health. When diet and exercise don’t work, statins- drugs that interfere with t...