Epidemiological evolution of chronic hepatitis, liver cirrhosis and liver cancer in the Republic of Moldova
Journal Title: One Health & Risk Management - Year 2021, Vol 2, Issue 2
Abstract
Introduction. The burden of liver diseases is a major health issue, being underestimated both at the national and international level. In the Republic of Moldova, there are over 70 thousand patients with chronic hepatitis and over 10 thousand people suffering from liver cirrhosis. 70% of patients with cirrhosis develop liver cancer. Over 2,000 patients die annually from complications caused by liver cirrhosis, and over 400 patients die due to primary liver cancer. Material and methods. The statistical analysis of 2000-2019 reports, presented by the Agency for Public Health, as well as of 3666 patient medical records retrieved from „Timofei Mosneaga” Republican Hospital, „Toma Ciorba” Clinical Hospital and “Sfinta Treime” Clinical Hospital was carried out. Results. 89290 cases of chronic hepatitis, liver cirrhosis and liver cancer have been officially registered. Most of them exhibited a viral etiology. The death rate was mostly recorded in patients aged 70-79. The mean age of patients with chronic hepatitis was 57.74±11.22, liver cirrhosis - 56.21±10.17, and liver cancer- 59.05±10.94. The risk factors included unprotected sex, use of sharp objects, scissors and syringes, noncompliance with dietary regimens, alcohol and tobacco use, etc. Close relatives were also investigated for the presence of viral markers in only 38.81% of cases of chronic hepatitis and in 24.37% patients with liver cirrhosis Conclusions. The study of common epidemiological evolution of chronic hepatitis, liver cirrhosis and primary liver cancer in the population, while considering the patient’s close relationship, might reduce both morbidity and medical and socio-economic impact.
Authors and Affiliations
Angela PARASCHIV
Keywords
Related Articles
- EP ID EP693649
- DOI 10.38045/ohrm.2021.2.11
- Views 148
- Downloads 0
Atypical presentation of a high-grade astrocytoma in a pediatric rheumatology Practice
Introduction. Hip pain is common in childhood. The main dilemma is to differentiate between benign conditions and those causing significant morbidity and mortality. Material and methods. A clinical case report of a to...
Acute flaccid paralysis in children in the post certification period of the Republic of Moldova as a country free of wild poliomyelitis
Introduction. Monitoring acute flaccid paralysis (AFP) is a key strategy used by the Global Polio Eradication Initiative (GPEI) in assessing the progress towards the global eradication goal. Material and methods. A cros...
The lichen genus Lepraria Ach. (Stereocaulaceae, lichenized Ascomycota) in Romania
Introduction. The genus Lepraria includes diffuse or indefinitely delimited species, always sterile, Lendemer (1) naming it „the most unusual member of the sterile lichen crusts”. According to Tonsberg (2), the leprarioi...
The efficacy of direct-acting antiviral therapy in patients with chronic hepatitis C
Introduction. Viral hepatitis C (HCV) is a significant global health problem. The risk of developing chronic HCV is up to 80% of patients, of whom 10-20% can develop liver cirrhosis or hepatocellular carcinoma which can...
Comparative analysis of long-eared owl (Asio otus) winter diet from two european cities – Chisinau (Republic of Moldova) and Bacau (Romania)
ntroduction. Many rodent species are important pests for agriculture and for urban areas. The long-eared owl is a predator that exerts constant pressure on rodent density. Material and methods. The studies were performe...