Epidemiological Risk Factors for Primary Ovarian Malignancy in Indian Population- A Case Control Study from a Tertiary Care Centre in Kerala
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 1
Abstract
Background: Ovarian malignancy accounts for almost 25 % of all gynaecological malignancies. Despite advances in molecular biology, surgery and chemotherapy long term survival of primary ovarian malignancy have hardly changed. Hence it is important to identify the risk factors. Though India comes under low incidence population for ovarian malignancy, age adjusted incidence rates are steadily increasing. A few studies only is reported from India and hence the need for this study. Methods: This is a case control study done at SAT Hospital, Government Medical College Thiruvananthapuram, Kerala over a period of one year. 50 women with a histological diagnosis of primary ovarian malignancy were studied. 50 age matched controls were taken. Data were collected by face to face interview. The data was coded and analysed using SPSS package. Case control analysis was done to find out the strength of association of individual risk factors. Odds ratio and corresponding 95% confidence interval were calculated. Results: Cases and controls were similar in socio-demographic variables. The significant risk factors were, age at menarche 13 or less, period of ovulation in postmenopausal woman more than 33 years and not underwent tubal ligation. Parity one or less, BMI more than 25 were not found as risk factors in our study. Conclusion: Ovarian carcinoma is hormone dependant with consistent association between ovulatory events or ovulation associated with ovarian inflammation. The importance of tubal ligation as a protective factor in ovarian carcinoma has to be highlighted
Authors and Affiliations
Anjali Devi. B
Keywords
Related Articles
- EP ID EP246331
- DOI -
- Views 29
- Downloads 0
Isolated Brain Involvement of Multiple Hydatid Cyst
Cerebral hydatid disease is rare accounting for only 1-2% of intracranial space occupying lesion and usually manifests as solitary cystic non enhancing lesions in the MCA territory distribution. It is even rarer to find...
The Study of Gynaecological Emergencies in Surgery
Aim &Objectives: To Study Quantum and Pattern the Gynecological problems in emergency surgery Materials & Methods: The Study Was Conducted Over 2000 patients. Of these twenty five patients amounting to 0.7 % of emergency...
Speciation of Enterococci to Predict Antibiotic Resistance Pattern: A Study from Teritiary Care Hospital
Background: Enterococci has recently emerged as a medically important pathogen causing hospital as well as community acquired infections. Detection of multi drug resistance is major health concern among the enterococci s...
Pattern of Renal Tumors: A Tertiary Care Center Experience over a decade
Aim: This study was undertaken to identify the age groups, gender distribution and different histopathological types of neoplastic lesions in nephrectomy specimens. Materials and Methods: This was a retrospective record...
Impact of Meditation in Memory of Health Science Students
Aim: The present study is to examine the changes in memory of health science students with meditation. Materials and Methods: Fifty healthy health science students in the age group of 17-23 were considered for the study....