EPIDEMIOLOGY OF GALL STONE DISEASE IN A TERTIARY CARE HOSPITAL- A CHANGING TREND IN CURRENT PERSPECTIVE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 75
Abstract
BACKGROUND Gallstones represent a significant burden for health care systems worldwide. Gallstones occur commonly in the western world. It is the leading cause of inpatient admissions for general surgical practice. The known epidemiology of gall stone like fat, fertile, female of forty seems to be changing now-a-days with shift towards thin young female patients and male sex. MATERIALS AND METHODS A total of 154 cholecystectomy procedures were performed in the time period between 15th Jan 2014 and 14th Jan 2015 in one year. All ultrasonographically proven gall stone disease patients undergoing cholecystectomy were included in our study. Out of 154 patients, 105 were female and 49 were male patients. All the included patients were interviewed with the help of questionnaire at the time of admission. Statistical analysis was performed using the SPSS Statistical Software Package. All values were expressed as percentage, mean ± standard deviation (SD). The values were evaluated using student’s ‘t’ test and Chi-square test was used for pair wise comparison and distribution significance. RESULTS Patients with gall stone disease are most commonly seen in thirties instead of forties as shown by numerous studies earlier. Male: female ratio is 1: 2.14, which has decreased from that described in earlier studies being 1: 4 to 1: 7. Maximum numbers of patients were overweight (BMI 25.00 - 29.99 kg/m2) and normal category (BMI 18.5 - 24.99 kg/m2) instead of obese persons (BMI ≥ 30.00 kg/m2) as seen in earlier studies. Family history of gall stone is not significantly associated (p > 0.05) with gall stone disease. Parity of one or more was significantly associated (p < 0.05) with gall stone disease in comparison to nullipara. CONCLUSION The present study revealed that the old known dictum that in a fat fertile female of forty presenting with right hypochondrium pain, always suspects of gall stone disease no more holds true in present scenario. The trend is changing with maximum patients presenting in their thirties with basal metabolic index (BMI) falling in overweight and normal category instead of obese along with narrowing male: female ratio. As at present there is trend of having two kids in the family, so parity of two being the commonest finding, the rule of multigravida being a predisposing factor no more holds true.
Authors and Affiliations
Pawan Kumar Singh, Prafull Kumar Arya, Harpreet Singh Khetarpal, Kanika Goyal, Tansila Din, Pankaj Srivastav, Sneha Singh
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