Epidemiology of Nervous System Tumors According to WHO 2007 Classification: A Report of 1,164 Cases from a Single Hospital
Journal Title: International Journal of Cancer Management - Year 2018, Vol 11, Issue 4
Abstract
Background: The central nervous system (CNS) belongs to heterogeneous group of glial and non-glial brain tumors. Increase in the frequency of brain and CNS tumors in Iran have been a cause for debate and concern. Objectives: The aim of this study was to estimate the frequency of the principal CNS cancers, using CNS cancer data records in a 7-year period in a hospital in Mashhad, Iran. Methods: This study is based on the records of department of surgical pathology, Razavi hospital, Mashhad, Iran. We analyzed 1,164 brain tumors and CNS cancers diagnosed from 2006 to 2013. It includes data on spinal cord tumors, primary brain such as lymphomas, which are hematological malignancies and metastatic tumors originating from external to the central nervous system. The frequency varies widely across this 7-year period. Results: The majority of brain tumor locations were frontal (13.2%), pituitary (11.7%), parietal (10.6%), Spinal (8.9%), Temporal (8%), and base of skull (6.3%). The most frequently reported histologies were meningiomas (33.6%) and glioblastomamultiforme (15.8%) that are strongly influenced the overall results. Higher numbers for glioblastoma, myxopapillaryependymoma, fibrillary astrocytoma, craniopharyngioma, hemangio-blastoma, oligodendro-glioma, and sarcoma were observed in male than in female patients. Meningioma, neurofibroma, and choroid plexus papilloma were the only tumors with a significant excess in female. Conclusions: We noted that higher frequency of brain tumors and CNS cancers occurred at age group of 51 to 60 years. Although data are hospital-based, is the first study to delineate the brain tumors and CNS cancers burden in north-east of Iran by age, sex, histology type, anatomical site, and laterality.
Authors and Affiliations
Narges Jafarzadeh, Arash Faal, Azra Izanloo, Farid Farrokhi, Reza Ziaolhagh, Hamid Reza Hashemian, Maliheh Dadgar Moghadam, Maryam Jafari-Rad, Farzad Bidouei, Kamran Ghaffarzadehgan
Keywords
Related Articles
- EP ID EP365776
- DOI 10.5812/ijcm.11462
- Views 78
- Downloads 0
Two Side Effects of Sutent Therapy in Renal Cell Carcinoma: A Case Report
Introduction Renal cell carcinoma (RCC) has known as the most frequent urological malignancy among adults, which occured mostly among male patients. Sunitinib malate (SUTENT<sup>®...
The Effect of Radiation Therapy on Hearing Loss in Patients with Head and Neck Cancer
Background: Radiotherapy is one of the important components of head and neck cancer (HNC) treatment. This treatment method may cause a variety of side effects like oral problems, swelling, and hearing loss. Objectives:...
The Effect of Para Aortic Lymph Node Dissection in Staging and Complete Cytoreductive Surgery of Ovarian Cancer
Objective: Lymphatic spread is a common feature of ovarian cancer both in early and advanced stages of the disease. There is also a controversial problem of the impact of para-aortic lymph node dissection between gynecol...
Investigation of Stigma Phenomenon in Cancer: A Grounded Theory Study
Background Adjustment to cancer as a stressful event is affected by bio-psycho-social factors. Objectives This study aimed to investigate stigma phenomenon, the process of formati...
Clinical Outcome and Prognostic Factors for Nasopharyngeal Carcinoma: A Single Institution Study in Iran
Background Evidence about survival of the patients with nasopharyngeal cancer is scant in our region and the aim of the current study was to determine clinico-pathological factors...