Ergothioneine: active principle of potential use in the agri-food andmedical-pharmaceutical industry
Journal Title: Biotecnología Vegetal - Year 2021, Vol 21, Issue 2
Abstract
Ergothioneine (ERG) is a water soluble amino acid, it is a strong and stable antioxidant. It hasthe ability to form complexes with metal cations helping to prevent the generation of ROS, itprotects cells from oxidative stress. ERG has received much attention as a therapeutic agentdue to its che mical prope rties, it accumulates in certain organs where its effect is required, ithas possible physiological functions as a cytoprotector with successful resultsin vitro andpossiblein vivo when analyzed on animal models, it acts in lung injury, hepatorenal dysfunction,and ischemia/reperfusion injury in the liver and small intestine and has potential beneficialeffects on vascular health. ERG exerts a protective effect against UV radiation, protects theskin from oxidation and DNA damage, protecting the mitochondrial membrane against oxidation.Much of the skin damage from UV radiation is mediated by the generation of ROS. The objectiveof this review was to deepen the knowledge of recent advances in the properties of ERG, itsquantification and the main properties that this component has to be used as an activeprinciple in the agrofood and medical-pharmaceutical industry due to its role as possibletherapeutic agent and powerful antioxidant
Authors and Affiliations
Alberto Renato Inca-Torres, Anabell del Rocío Urbina-Salazar, Juan Bautista
Keywords
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