ESTIMATION THE ANTIBACTERIAL EFFECT OF CURCUMIN AND ROSEMARY AMONG PATIENTS WITH DENTAL CARIES IN VITRO
Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2019, Vol 12, Issue 3
Abstract
Objective: The aim is to estimate the effect of curcumin and rosemary as antibacterial agents among dental caries cases. Methods: Samples of saliva were randomly collected from 40 patients in Al-Furat General Hospital who attended the hospital from July to September 2018. Swabs were cultured on blood agar at 37°C for 24 h and then subcultured in mannitol salt agar and trypticase soy broth at 37°C for 24 h. Different concentrations of aqueous extract curcumin solution (0.1, 0.3, 0.5, and 1 mg/ml) and rosemary solution (1 g/ml) were prepared and added to the bacterial culture. Later, minimum inhibition zones of the bacterial cultures were determined. Results: The results showed that there were 25 cases of Streptococcus mutans, 10 cases of Staphylococcus aureus, 3 cases of anaerobic bacteria, and 2 cases of normal flora among 40 culturing swabs of bacteria. Aqueous extract of curcumin showed antibacterial effect with concentrations (0.1, 0.3, 0.5, and 1 mg/ml) against oral bacteria; nevertheless, these bacteria were resistant to the aqueous extract of rosemary with concentration 1 g/ml. Conclusion: It can be concluded that curcumin can be an effective antibacterial agent against dental caries disease and its effect increases positively in relation to its concentration. On the other hand, rosemary with 1 g/ml concentration did not show any effect on oral bacteria.
Authors and Affiliations
EHAN ABDULHADI AL-SHARIFI, ASIA ABED AL-MAHMOOD, SUMAYAH AL-MAHMOOD
Keywords
Related Articles
- EP ID EP603872
- DOI -
- Views 133
- Downloads 0
STABILITY-INDICATING METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF ROSUVASTATIN CALCIUM IN BULK AND TABLET FORMULATION BY REVERSE-PHASE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY
Objective: The present work was focused on the development and validation of reverse-phase high-performance liquid chromatography (RP-HPLC) method which is simple, rapid, precise, accurate, sensitive, economical, and sta...
PHARMACOLOGICAL POTENTIALS OF PYRIMIDINE DERIVATIVE: A REVIEW
The chemistry of pyrimidine derivatives plays an important role in the field of drugs, agriculture chemicals and many biological processes. The chemistry of pyrimidine is a provoking field. In recent decades, a large num...
A STUDY ON FORMULATION AND ACCEPTABILITY OF ANTI-COLD MOCKTAILS WITH VITAMIN C ENRICHED INGREDIENTS
Objectives: Common cold is a widespread respiratory infection among all age groups. This creates a great nuisance and discomfort making a person feels ill. Common cold can also be treated with home-made remedies. The stu...
CYTOTOXIC EFFECT OF CORCHORUS DEPRESSUS AGAINST HEPG2 AND HLE HUMAN LIVER CANCER CELLS
Objective: The present study was designed to examine the cytotoxic effects of methanolic extract of aerial parts of Corchorus depressus and hexane, chloroform, ethyl acetate, and aqueous fractions of the same extract in...
DEVELOPMENT AND EVALUATION OF FLOATING TABLET OF METOPROLOL SUCCINATE FOR INCREASED BIOAVAILABILITY VIA IN VIVO STUDY
Objective: This study was performed to formulate a floating tablet using hydrophobic glyceryl behenate (GB) and hydrophilic hydroxypropyl methylcellulose polymers, optimization of the same for retention in stomach and su...