Ethyl acetate. Documentation
Journal Title: Podstawy i Metody Oceny Środowiska Pracy - Year 2013, Vol 29, Issue 2
Abstract
Ethyl acetate is colourless, transparent liquid with a fruity odour. It is one of the most widely used solvents and extractants in various industrial applications. Ethyl acetate is absorbed well by inhalation and rapidly hydrolyzed to ethanol and acetic acid, which are metabolized further. Its acute toxicity is very low. The critical effect in human is irritation of the upper respiratory tract and eyes after exposure to concentrations of over 1468 mg/m[sup]3[/sup]. In high, almost lethal concentrations, ethyl acetate is narcotic and causes lung damage. Daily application of ethyl acetate led to defatting of the skin and damage to the stratum corneum of tested persons. Studies of volunteers exposed to ethyl acetate showed its irritating effect on the eyes and airways after exposure to a concentration of 1468 mg/m[sup]3[/sup] (LOAEL). Following the above data, the MAC value for ethyl acetate was established at 734 mg/m3 and the value of STEL at 1468 mg/m[sup]3[/sup]. The proposed values of the hygienic standards should protect workers from harmful effects of ethyl acetate on their eyes, airways and nervous system. An additional notation for ethyl acetate: “I” – an irritant substance.
Authors and Affiliations
Renata Soćko
Keywords
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