Etiological profile and antibiotic sensitivity pattern of uropathogens in children at a teaching hospital, Thrissur
Journal Title: National Journal of Research in Community Medicine - Year 2018, Vol 7, Issue 7
Abstract
Background: Urinary tract infection (UTI) is very common among community-based and hospitalized children. Approximately 3-8% of girls and 1% of boys are diagnosed with UTI, and may lead to serious complications if not treated appropriately. Empirical treatment of UTI with antibiotics leads to antibiotic resistance. The choice of antibiotics should be based on a basic knowledge about current causative uropathogens and their susceptibility patterns. Objectives: To determine the aetiologic profile and antibiotic susceptibility of uropathogens in children at a teaching hospital. Methodology: A record-based retrospective study was conducted using a total of 129 positive urine culture and sensitivity reports (bacterial count >105 CFU / ml of urine) of children with suspected UTI between February 2011 and January 2012 at a teaching hospital in Thrissur. Data were entered using Microsoft Excel 97, and analyzed by Epi-Info, EZR. Results: E. coli (2(63.6%)) and Klebsiella(23(17.8%))were the commonest uropathogens followed by Enterococci (8.5%) and Proteus (6.2%). Infants (54(41.9%)) were more frequently affected than the older age-groups. More males (74(57.4%)) were affected as compared to females. E.coli isolates were found predominantly in boys while Klebsiella isolates were more frequent in girls. Over 80% of both isolates were sensitive to Amikacin, Cefoperazone and Piperacillin-Tazobactam while >70% were sensitive to Gentamicin and Nitrofurantoin. Klebsiella also showed more than 80% sensitivity to Ciprofloxacin and Norfloxacin. Both organisms were highly (>90%) resistant to ampicillin. Conclusion: E.coli was the commonest uropathogen, followed by Klebsiella. Treatment strategies and antibiotic policy should be informed by the etiology and sensitivity patterns of uropathogens.
Authors and Affiliations
Catherine Simon, Parvathy VK, Liaquat Roopesh Johnson, Rajany Jose
Keywords
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- EP ID EP527833
- DOI 10.26727/NJRCM.2018.7.4.260-265
- Views 73
- Downloads 0
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