Evaluate the action of the aqueous extract of the medicinal plant Goji Berry (Lyciumbarbarum) on biochemical and hematological parameters in Wistar rats
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 5
Abstract
Medicinal plants were discovered by man through the food demand, and since then, are used empirically for the treatment of conditions, or in the form of infusion, decoction or another, with the purpose to cure or at least alleviate the suffering of the patient has great historical importance, and also at the present time for various population groups.The use of plants with therapeutic properties in treating diseases is called herbal medicine. The species Lyciumbarbarum, known as Goji Berry isa solanaceafamily plant found in China and Himalayan regions, positioned for millenniums at the top of the table of the 8000 Chinese herbs and healing food. In recent years, the hepatotoxic effects and interactions with anticoagulants have been reported as adverse Allergic reactions photodermatitis type and immediate type reactions have also been described. The objective of this study was to evaluate the action of the aqueous extract of the medicinal plant Goji Berry (Lyciumbarbarum) on biochemical and hematological parameters in rats. 30 Rattus norvegicus were divided into two groups, one with exposure Goji Berry (200mg / kg orally) and a negative control (distilled water. We assessed the hematological profile, complete blood count and biochemical determination of various plasma constituents in acute(48h) and chronic (72h) phases.Statistical analyzes were performed using GraphPad Prism version 5.0 software. For data analysis we used the Student t test, expressed as mean and standard deviation. For all tests was considered a 5% significance level.The results showed that there was no significant difference between the group exposed to the treatment when compared to the negative control group. The data suggest that the aqueous extract of Lyciumbarbarum (Gojji berry) used at the dose of 200 mg / kg shows no effect on hematological and biochemical parameter.
Authors and Affiliations
Leide Maria Soares deSousa, Wcleubianne Matias Nascimento1, Juliana de Almeida Rodrigues Franco Netto, Danniel Cabral Leão Ferreira, Samylla Miranda Monte2, Gêrda Coelho E Silva, Fabrício Pires Moura Do Amaral2 ,, RosemarieBrandim Marques, Antônio Luiz Martins Maia Filho2
Keywords
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- EP ID EP386649
- DOI 10.9790/3008-1105044852
- Views 80
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