Evaluation of Abdominal Organs in Children with Sickle Cell Anemia using Ultrasonography
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 3
Abstract
Abstract: Sickle-cell disease (SCD), also known as sickle-cell anemia (SCA), is a hereditary blood disorder, caused by an abnormality in the oxygen-carrying protein hemoglobin found in red blood cells. This leads to a propensity for the cells to assume an abnormal, rigid, sickle-like shape under certain circumstances. Sickle-cell disease is associated with a number of acute and chronic health problems, such as severe infections, attacks of severe pain ("sickle-cell crisis"), stroke, and an increased risk of death.The study was aimed to evaluate the abdominal organs in children with sickle cell anemia using ultrasonography. This was cross sectional descriptive study; conducted in a total of 103 patients with sickle cell anemia, their age was range 10 months -16 years (mean age 6.1 years ± 4.3 SD), in different hospital in Khartoum from January - August 2016. All patients scanned by ultrasound according to international guidance and protocol, their ultrasound findings and history was recorded in data collection sheet and these data was analyzed by Statistical package of social sciences program version 15. The commonest transabdominal ultrasound finding in this study was splenic abnormality in 74 (71.9%) flowed by hepatomegaly in 53 (51.5%) patient, gallbladder abnormality in 22 patients (21.3%), and enlarged kidneys in 23 patients (22.3%).There was positive relation between spleen size and the duration of disease, in early stage of disease the spleen is enlarge and after that become small with time until disappear in adulthood.This study provides that ultrasound have excellent role in detected abdominal abnormality in sickle cell anemia patients and to follow the complications of disease. The study recommended that, ultrasound should be used as routine exam to follow the stages of disease because it is noninvasive and repeatable. Keywords:Sickle-cell disease (SCD), blood disorder, ultrasonography, abdominal organs
Authors and Affiliations
Nosiba H. M. Ahmed, Ahmed Abdelrahim Mohammed, Ala Mohammed Abd Elgyoum
Demographical Evaluation of Type 2 Diabetes Mellitus and Effect of Prescribed Anti Diabetic Drugs on Maintaining Optimal Glycemic Levels in Diabetic Patients: An Observational Study
Abstract: The aim of the study was to evaluate Type 2 Diabetes Mellitus patients demographically and Effect of Prescribed Anti Diabetic Drugs in maintaining optimal glycemic levels in diabetic patients attending Medicine...
Autoimmune Thyroiditis in Polycystic ovarian syndrome cases
Abstract: Polycystic ovarian syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age.In recent years, a number of publications have reported close association between autoimmune thyroid...
A Study on the Operative Management of Biliary Strictures
Biliary strictures both benign and malignant, remain one of the most difficult problem encountered by the surgeons. The vast majority of bile duct strictures are iatrogenic and occur mainly as a complication of cholecyst...
Comparison of Histopathology/FNAC and CT Scan of Cases of Abdominal Tuberculosis Coming to a Tertiary Care Hospital in India
Abdominal tuberculosis is a most common type of extra-pulmonary tuberculosis. So it is thought worthwhile to study the various clinical presentations of abdominal tuberculosis, its evaluation and diagnosis with the help...
Impact of Haemoglobin Variants AS and AC on Asymptomatic Falciparum Malaria among Adults in Iwo, Southwestern Nigeria
Several studies have shown that haemoglobin (Hb) variants AS and AC are associated with resistance to severe falciparum malaria infection. However, reports on association between these haemoglobin variants and asymptomat...