Evaluation of acetylcholinesterase inhibitory activity of Brahmi nei, a Siddha formulation using in - vitro techniques.
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH IN MEDICAL SCIENCES - Year 2018, Vol 4, Issue 6
Abstract
Acetylcholine is the chief organic chemical responsible for the function of brain and various other activities of human body. It plays a major role in neurotransmission and performs its function in both Central nervous system and peripheral nervous system. Alzheimer’s disease, Myasthenia gravis, Dementia are some of the worst illness caused due to the disturbances in the activity of acetylcholine. In our Siddha text many formulations have been mentioned for the treatment of neurological disorders. Brahmi nei (medicated ghee) is one among them and being used from ancient times to cure neurological disorders. The chief ingredient of this formulation is Bacopamonnieri. The prevalence of brain disorders are highly increasing nowadays and it seems as a worsen thing in society. In order to overcome these disorders a study was conducted in Brahminei to evaluate its acetylcholinesterase inhibitory activity using in vitro techniques. The results are confirming that Brahminei is having strong acetylcholinesterase inhibitory activity. This study creates the platform for the therapeutic use of Brahmi Nei to treat brain disorders in future.
Authors and Affiliations
G. Arunkumar*1 , J. Kingsley2 , Dr. A. Mariappan3 , Dr. S. Sivakkumar4 , Dr. S. Visweswaran5 , Dr. V. Banumathi6 .
Keywords
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- EP ID EP563085
- DOI 10.22192/ijcrms.2018.04.06.013
- Views 131
- Downloads 0
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