Evaluation of Anti-bacterial Activity of Silybum marianum against Pathogenic and Resistant Bacteria
Journal Title: European Journal of Medicinal Plants - Year 2016, Vol 13, Issue 4
Abstract
Aims: Our arsenal of antibiotics is running low due to overuse and misuse of these lifesaving drugs. Much research is needed on medicinal plants to look for drugs to tackle this issue Methodology: so antibacterial activity of organic extracts of Silybum marianum was evaluated against Methicillin-resistant Staphylococcus aureus (MRSA), resistant E. coli, ATCC 12361, ATCC 12466 and ATCC 13581. Inhibition of bacterial growth was determined using agar well diffusion methods. Results: Among all assayed organic extracts only Dimethylformamide presented highest activities against all tested strains except resistant E. coli. Dimethylformamide and Methanol showed better activity than cephradine against ACTT 13581. The Dichloromethane extract showed no antibacterial activity against any strains. Methanol and Isopropyl Alcohol showed moderate activities against all tested strains. S. marianum would be an interesting topic for further study and possibly for an alternative treatment for resistant and pathogenic bacterial infections.
Authors and Affiliations
Amoos Bajwa, Sheraz Tariq, Alamgeer Yuchi, Rizwan Hafeez, Amna Arshad, Muhammad Zaman, Tahir Aqeel, Muhammad Naveed Mushtaq
Keywords
Related Articles
- EP ID EP349742
- DOI 10.9734/EJMP/2016/24732
- Views 73
- Downloads 0
Antibacterial Properties of the Leaf Extracts of Anthocleista djalonensis A. Chev on Some Pathogenic Organisms
Aims: To determine the antibacterial effect of methanol, petroleum ether and hot water extracts of Anthocleista djalonensis A. Chev on some pathogenic bacteria and to establish the use of the leaf extract in herbal medic...
Effect of Aqueous Leaf Extract of Ocimum gratissimum on Antiretroviral Drug-Induced Hepatotoxicity in Rats
Aim: Hepatotoxicity, among other adverse effects, constitutes one of the greatest impediments to successful antiretroviral drug therapy (ART) in HIV/AIDS patients. The main objective of the study was to determine if the...
Carcinogen Metabolizing Enzymes: Modulation of Their Activities in Liver, Lung and Stomach by Thymoquinone
Background: Thymoquinone (TQ), the bioactive constituent of black seed (Nigella sativa), has been shown to inhibit the growth of various human cancerous cells both in vitro and in vivo. Aim: To characterize the effects...
Evaluation of Antidiabetic and Hypolipidemic Efficacy of Various Fractions of Heartwood of Pterocarpus marsupium (Fabaceae) on Alloxan Induced Diabetic Rats
Aim: The objective of the present work is to study the antidiabetic and hypolipidemic effect of different fractions of heart wood of Pterocarpus marsupium in alloxan induced diabetic rats. Methodology: Diabetes was induc...
Study of Cytotoxic, Thrombolytic and Anthelmintic Activity of Extract of Neolamarckia cadamba (Roxb.) Leave
Aim of the Study: The study was aimed to evaluate the cytotoxic, thrombolytic and anthelmintic activity of methanolic extract of the stem of Neolamarckia cadamba (Roxb.). Place and Duration of Study: The research was ca...