Evaluation of Anti-Depressentactivity of Ethanol extract of DrypetusRoxburgii
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 6
Abstract
Depression is the leading cause of disability and the fourth leading contributor to the global burden of disease in 2000. Today, depression is already the secondcause in the age category 15-44 years for both sexes combined. The present study was designed to evaluate the anti‐depressant activity of ethanol extract of the leaves of Drypetusroxburgii belonging to family Euphorbiaceae by using actophotometer and forced swimming test (FST) in Swiss albino mice. The albino mice were treated with ethanol extract at a dose of 500mg/kg orally and behaviour was observed on actophotometer and FST. The results showed that ethanol extract at a dose of 500mg/kg of the leaves of Drypetusroxburgii has anti-depressant activity.
Authors and Affiliations
Akshara1 . , Krupanidhi A. M, Ashok R . Chanchi2, Akshaykumar K3 ,, Yashaswini . T4
Keywords
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