EVALUATION OF ANTI-DIARRHOEAL ACTIVITY OF AMARANTHUS TRICOLOR LINN IN EXPERIMENTAL ANIMALS
Journal Title: Innoriginal: International Journal Of Sciences - Year 2015, Vol 2, Issue 1
Abstract
Objective: To evaluate the anti-diarrhoeal activity of different extracts of the leaves of Amaranthus tricolor Linn. using different animal models. Methods: The shade dried leaves of Amaranthus tricolor.L was extracted with ethanol (95%) and then partitioned by petroleum ether, chloroform and ethyl acetate. The anti-diarrhoeal activity of various extracts of Amaranthus tricolor was evaluated using castor oil induced diarrheal model in rats, castor oil-induced enter pooling in rats and gastrointestinal motility test in rats. Results: The results revealed that the ethanolic extract and ethyl acetate fractions significantly inhibited diarrhea and reduced the distance travelled by the activated charcoal in intestine in rats. Conclusion: Our results showed that Amaranthus tricolor displayed potent anti-diarrhoeal properties, supporting the ethno-medical use given to this plant for treatment of diseases.
Authors and Affiliations
Samsul Alam, Krupanidhi K, K. R. S Sambasiva Rao
Keywords
Related Articles
- EP ID EP444235
- DOI -
- Views 125
- Downloads 0
A DRUG:AMPHOTERICIN B OF CLINICAL ADVANTAGES AND IT’S COMPLICATIONS -A REVIEW
Amphotericin B (Amp B) was discovered by some researchers Gold et al., (1956) [1], who were studying a strain of Streptomyces nodosus, an aerobic actinomycete, obtained from the Orinoco River Valley of Venezuela. The ant...
PHARMACEUTICAL STUDIES OF ATENOLOL BRANDS: INTERCHANGEABILITY BETWEEN ATENOLOL (100 MG) TABLETS BRANDS MARKETED IN LIBYA
Hypertension is the most widely distributed cardiovascular diseases in Libyan regions. Atenolol is one of most used β-blockers in Libya as the first line in treatment of hypertension. Therefore, In Libya there are severa...
STRESS AND IMMUNITY: BRIEF REVIEW OF MECHANISMS IN PSYCHONEUROIMMUNOLOGY
Psychoneuroimmunology is the term used for the interaction of the psychological stimulus with the immune system. The main objective of this paper is to have a thorough review of the mechanisms behind the immune changes d...
FAST DISSOLVING TABLETS OF ACECLOFENAC: DEVELOPMENT AND OPTIMIZATION
Objective: The present research works was aimed to develope and optimize fast dissolving tablets of aceclofenac via 32 full factorial designs to investigate the influence of formulation variables. Methods: Different conc...
PREVALENCE OF DEPRESSION AMONG ELDERLY PEOPLE
Background: Depression is a mood disturbance characterized by exaggerated feelings to sadness, despair, lowered self esteem, loss of interest in former activities and pessimistic thoughts. The incidence of increased de...