Evaluation of Anti-Inflammatory Activity of 3-(1-Methoxy Napthalen-2-yl)-5-Phenylisoxazole by Using Passive Anaphylaxis in Rats.
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2017, Vol 12, Issue 6
Abstract
The structures of newly synthesized compounds were established on the basis of elemental analyses, IR. The newly synthesized heterocyles were characterized based on their chemical properties and spectroscopic data, and were found to difference in the reading prior to and after challenge represents the edema volume and the anti-anaphylactic effect was expressed as the percentage inhibition by using passive paw anaphylaxis in rats. Isoxazole derivatives have been prepared by condensing alpha-naphthol with acetic unhydride respectively. While compounds have been synthesized by the reaction of 3-(1-methoxy napthalen-2-yl)-5- phenylisoxazole.The compounds were screened for their anti-inflammatory activities.
Authors and Affiliations
Kumawat. J. A, Dr. Angadi. S. S, Padve D. A, Sakore A. R
Keywords
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