Evaluation of Bacteriophage Therapy against Bacterial Pathogens (Pseudomonas, Bacillus)
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2017, Vol 12, Issue 5
Abstract
The use of bacteriophage to treat bacterial infection is a novel approach and is being seriously considered. Bacteriphage had the potential to kill the bacteria that causes infection in humans as well as agriculturally important plants and animals. Phage therapy is a form of biological control, the use of one organism to suppress another and reduction in the usage of chemical agents against pest species, which in the case of phage, means a reduction in the usage of chemical antibiotics. Brinjal plant is used for this phage therapy experiment; phage is isolated from the sewage and was confirmed by plaque assay method. Various concentrations of phages were treated with brinjal plant. Plant protected with phage injection exhibited no symptoms when compared to unprotected one. This protection could be attributed to the marked reduction of the pathogen load in stem of the brinjal plant in response to the presence of persistence of phage.The aim of present study is to treat the bacterial infections using specific bacteriophages. Since bacteria developed resistant to majority of antibiotics, phages are extensively used.
Authors and Affiliations
Sarojini. G1, Sripriya. M2
Keywords
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- EP ID EP391242
- DOI 10.9790/3008-1205058790
- Views 65
- Downloads 0
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