Evaluation of anti-tubercular activity of leaves of vitex negundo by in –vitro method
Journal Title: International Journal of Research in Pharmacology & Pharmacotherapeutics (IJRPP) - Year 2017, Vol 6, Issue 3
Abstract
One third of the world’s population is thought to be infected with tuberculosis. As the searches are going on anti- tubercular natural flavonoids. The leaves of Vitex negundo were found to be rich in phytochemical constituents with may have immense pharmacological actions. The literature survey revealed the presences of alkaloids, glycosides, flavonoids, tannins, steroids and terpenoids, carbohydrates, proteins in the entire plant in which flavonoids are responsible for anti-tubercular activity. The results of the present study indicates that different extracts of leaves of Vitex negundo exhibited anti-tubercular activity against M.tuberculosis (H37RV Strain) at the doses of 100µg/ml and 50 µg/ml shows the inhibition of growth among all 8 concentrations such as 0.8,1.6,3.12,6.25,12.5,25,50,100 µg/ml by using Alamar blue assay method for in-vitro evaluation of anti-tubercular activity.
Authors and Affiliations
Bhargaviganiwada Bhargaviganiwada
Keywords
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