Evaluation of anti-ulcer activity of ethanolic extract of Dactyloctenium aegyptium
Journal Title: International Journal of Research in Pharmacology & Pharmacotherapeutics (IJRPP) - Year 2016, Vol 5, Issue 1
Abstract
The ethanolic extract of Dactyloctenium aegyptium was investigated for its anti-ulcer activity against aspirin plus pylorus ligation induced gastric ulcer in rats, HCl -Ethanol induced ulcer in mice and water immersion stress induced ulcer in rats at 300 mg/kg body weight. p. o. A significant (P<0.01, P<0.001) anti-ulcer activity was observed in all the models. Pylorus ligation showed significant (P<0.01) reduction in gastric volume, free acidity and ulcer index as compared to control. It also showed 89.71% ulcer inhibition in HCl- Ethanol induced ulcer and 95.3% ulcer protection index in stress induced ulcer. This present study indicates that Dactyloctenium aegyptium extract has potential anti ulcer activity in the three models tested.
Authors and Affiliations
Veeresh Kumar p
Keywords
Related Articles
- EP ID EP408354
- DOI -
- Views 115
- Downloads 0
Literary approach to Annona muricata and its role in cancer- A review
1Annona muricata L. belongs to the family of Annonaceae has a wide spread pantropical distribution and has been pridely known as corossol. 20Annonaceous acetogenins are a new class of compounds that have been reported t...
ANTIUROLITHIATIC ACTIVITY OF ACTIVITY OF TECOMA STANS LEAF EXTRACT
Herbal medicines offer vast scope for the successful treatment of urolithiasis. Although most remedies were herbal and proved useful, a systematic scientific evaluation has been reported for only few remedies. Tecoma st...
Hypoglycemic effect of ethanolic extract of Hedychium coronarium linn., rhizome in alloxan induced diabetes in rat model
Purpose To study the Hypoglycemic effect of ethanolic extract of Hedychium coronarium linn., rhizome in Alloxan induced diabetes in rat model. Methods The preliminary photochemical studies were carried out on the crude...
Nephroprotective activity of heliotropium indicum in rifampicin induced nephrotoxicity rats
The nephroprotective effect of whole plant of ethanolic extract of Heliotropium indicum was confirmed by our study. In Rifampicin treated group urea, uric acid and creatinine levels are increased in serum and urine where...
Impact of educational intervention on knowledge, attitude, perceptions of pharmacovigilance and adverse drug reactions in fifth term medical students and their feed back
Aim of the study-The Study was designed to assess the awareness of Pharmacovigilance and Adverse Drug Reaction (ADR’s) reporting and to evaluate the impact of an educational intervention. Materials and methods-This was...