Evaluation of Antimicrobial Efficacy of Graphene Silver Composite Nanoparticles against E. faecalis as Root Canal Irrigant: An ex-vivo study
Journal Title: International Journal of Pharmaceutical and Medicinal Reserach - Year 2015, Vol 3, Issue 4
Abstract
Aim: The aim of this in vitro study was to evaluate the antimicrobial effectiveness of Graphene Silver Composite Nanoparticles as an endodontic irrigation solution. Methodology: Thirty caries-free, singlerooted, mandibular premolar human teeth were prepared in a similar method to that used for in vivo root canal treatment. The root canals were inoculated with a suspension containing E. Faecalis bacteria. The teeth were then randomly divided into three groups. Each group was irrigated with one of the following solutions: Saline (control), Graphene Silver Composite Nanoparticles and Sodium hypochlorite (3%). Antimicrobial effectiveness was evaluated immediately after irrigation and again after 3 days, by counting colony forming units on blood agar plates. Results: The percentage reduction of E. Faecalis in Saline was 21.64 %, with Sodium hypochlorite it was 80.40% and the maximum reduction was observed in Graphene Silver Composite Nanoparticles with 86.85%. Conclusion: Within the confines of this study Graphene Silver Composite Nanoparticles demonstrated maximum antimicrobial effectiveness against E. Faecalis bacteria.
Authors and Affiliations
Sharma DK. , Bhat M. , Kumar V. , Mazumder D. , Singh SV. , Bansal M.
Keywords
Related Articles
- EP ID EP31503
- DOI -
- Views 360
- Downloads 1
Herbal remedies used in the treatment of liver disease and development of those remedies by the help of micro-propagation: A review
The 21st century has seen a paradigm shift towards therapeutic evaluation of herbal products in liver diseases by carefully synergizing the strengths of the traditional systems of medicine with that of the modern concept...
Development and evaluation of buccal film of norethindrone for birth-control
Norethindrone is the class of progesterone which is used to prevent pregnancy. The plasma levels were considerably higher in women than men, especially at low dose levels. The plasma half –life of norethindrone is a...
Stress management techniques among female academic staff to overcome occupational stress at universities in Khartoum state
The present study was aimed to observe stress management techniques among female academic staff to overcome occupational stress at universities in Khartoum state. Materials and methods: The sampling frame for the study...
Technology transfer in Pharmaceutical Industry: A review
The term technology transfer refers to the process of movement of technology from one unit to another. The transfer may be said to be successful if the receiving unit and the transferee can effectively utilize the tech...
Do ‘Patient Management Problems (PMP)’ act as ‘Motivators’ in Internal Assessment examinations?
Context: Problem based learning when used with adult learners stimulates deep learning. Internal motivators are essential as envisaged in principles of Adult learning .In educational spiral, the Internal assessment (fo...