Evaluation of Antimicrobial Efficacy of Graphene Silver Composite Nanoparticles against E. faecalis as Root Canal Irrigant: An ex-vivo study
Journal Title: International Journal of Pharmaceutical and Medicinal Reserach - Year 2015, Vol 3, Issue 4
Abstract
Aim: The aim of this in vitro study was to evaluate the antimicrobial effectiveness of Graphene Silver Composite Nanoparticles as an endodontic irrigation solution. Methodology: Thirty caries-free, singlerooted, mandibular premolar human teeth were prepared in a similar method to that used for in vivo root canal treatment. The root canals were inoculated with a suspension containing E. Faecalis bacteria. The teeth were then randomly divided into three groups. Each group was irrigated with one of the following solutions: Saline (control), Graphene Silver Composite Nanoparticles and Sodium hypochlorite (3%). Antimicrobial effectiveness was evaluated immediately after irrigation and again after 3 days, by counting colony forming units on blood agar plates. Results: The percentage reduction of E. Faecalis in Saline was 21.64 %, with Sodium hypochlorite it was 80.40% and the maximum reduction was observed in Graphene Silver Composite Nanoparticles with 86.85%. Conclusion: Within the confines of this study Graphene Silver Composite Nanoparticles demonstrated maximum antimicrobial effectiveness against E. Faecalis bacteria.
Authors and Affiliations
Sharma DK. , Bhat M. , Kumar V. , Mazumder D. , Singh SV. , Bansal M.
Keywords
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Evaluation of Antimicrobial Efficacy of Graphene Silver Composite Nanoparticles against E. faecalis as Root Canal Irrigant: An ex-vivo study
Aim: The aim of this in vitro study was to evaluate the antimicrobial effectiveness of Graphene Silver Composite Nanoparticles as an endodontic irrigation solution. Methodology: Thirty caries-free, singlerooted, mandibu...