EVALUATION OF ANTIPYRETIC ACTIVITY OF BRUHAT HINGULESHWARA RASA
Journal Title: Journal of Biological and Scientific Opinion - Year 2017, Vol 5, Issue 4
Abstract
Abnormal food habits (mithyaahara), abnormal style of living (mithyavihara), and other factors disturbs Jatharagni, which leads to jwara (fever) &vedana (pain). Bruhat Hinguleshwara Rasa is mentioned in Bhaisajya Ratnavali, having a multidimensional therapeutic indication i.e. Jwarahara and Vedananashak& this activity have encouraged to evaluate the antipyretic activity. Albino rats were divided into three groups and distributed 06 in each group. Test drug (Group-I), Standard drug (Group-II) and Group-III (Propylene glycol).Anti-pyretic study was done by Yeast induced method. Significant antipyretic activity was observed in Test Drug (GI), and Standard Drug (GII). But in Test Drug (GI) it was highly significant than Control Drug (GIII). In test drug antipyretic activity was observed from 1st hr to 6th hr, while in standard it was from 1st hr to 5th hr. Bruhat Hinguleshwara Rasa has shown significant and sustained Anti- pyretic Activity. This study has provided evidence& given scope for clinical research.
Authors and Affiliations
Shivaleela . , Kashinath Hadimur, R. S. Sarashetti, K A Patil
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