Evaluation of antistress activity of Cassia auriculata seed extract
Journal Title: UNKNOWN - Year 2018, Vol 7, Issue 2
Abstract
Objective: The present study was designed to investigate the anti-stress activity of Cassia auriculata ethanolic seed extract in mice. Methodology: The anti-stress effect was evaluated by using Elevated plus maze (EPM), Force swimming test (FST) and Tail suspension test (TST). The ECS at a doses (250,500 and 1000 mg/kg p.o.) and standard (diazepam 2 mg/kg i.p and fluoxetine 20 mg/kg i.p) was administered. Results: The extract showed the increased in the number of entries and time spent in open arm in Elevated plus maze and decreased in the immobility time in both Force swimming test and Tail suspension test. Conclusion: The effect of ESC on animal behavior was concordant with a significant regulation of GABA and stress hormones. Therefore, this study was attempted to demonstrate the preventive potential of ECS against stress disorders at in vivo levels.
Authors and Affiliations
Shravan Kumar Nanumala, B. Varsha Priyanka, N Divya, S Shalini, S. Sanjay Singh, T Haripriya
Keywords
Related Articles
- EP ID EP589756
- DOI -
- Views 42
- Downloads 0
Baillonella toxisperma improves sexual performance and protects against stress-induced reproductive dysfunction in male Wistar rats
Baillonella toxisperma Pierre (Sapotaceae) is a medicinal plant widely used in Central Africa against several diseases including erectile dysfunction and male infertility. However, no study dealing with these male reprod...
Aphrodisiac property of aerial parts of Trianthema decandra Linn.
Aim of the study is to identify and evaluate the active constituents present in the aerial parts of Trianthema decandra Linn. The fresh aerial parts of plant were collected, dried under shade, coarsely powdered and succe...
Evaluation of antioxidant activity of some wild edible fruits collected from Boda and Kolli hills
Free radicals or highly reactive oxygen species are capable of inducing oxidative damage to human body. Antioxidants are the compounds which terminate the attack of reactive species and reduce the risk of diseases; hence...
Ethnomedicinal survey of plants used by tribal in Lalgarh forest range, W.B., India
Exploration of the traditional knowledge of the indigenous people is very important for revealing the uses of plants and plant parts for medicinal purpose. Once the medicinal use of these plants is known, their active in...
Quantitative analysis of lycopene content in two commercially available tomato sauces: HPTLC based quality check
The demand for high nutritional quality food is increasing because of the commercial opportunities offered by such products due to their visual and functional properties, increasing consumer awareness for the relationshi...