“Evaluation of ASO test and correlation with clinical request in a tertiary care teaching hospital: An insight study”
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 9
Abstract
ntroduction:Post streptococcal diseases caused by beta haemolytic group A streptococcus usually confirmed by antistreptolysin O test. The aim of this study is evaluation of ASO titre and correlation with clinical request. Methodology: It is a retrospective and descriptive study conducted at the Central laboratory of Department of Microbiology, Malda Medical College. We analyzed all requests during last one year. From sera, obtained from patient, we done qualitative test to determine ASO positive sera and semiquantitative test to determine ASO titre.Results: There were 586 requests of ASO titration during the last one year of study. The mean age was 32.5 years (ranging from 5 to 60 years), with a female predominance (53.9 %).Cardiac symptoms were most common request (54.9%). Most common frequency of ASO request was found from age group 16 to 30 years (43.6 %). Out of 586 tests, 220 tests shows positive result means ASO titre level more than >200 IU/ml and 366 tests shows negative result means ASO titre level less than <200 IU/ml Most common titre level was found >200<400 IU/ml.Conclusion:ASO test is cheaper and easy to perform even in rural settings.The test can provide baseline information for use in diagnosis though it has not been deployed in many clinical settings in India and other developing countries.ASO test is very helpful when culture is negative and patient already has taken antibiotics.
Authors and Affiliations
Dr. Puronjay Saha, Dr. Arnab Kumar Mandal, Dr. Tapati Mondal, Prof. Pratip Kumar Kundu
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