EVALUATION OF CARCINO EMBRYONIC ANTIGEN (CEA) AND CARBOHYDRATE ANTIGEN (CA19-9) IN MONITORING OF TREATMENT RESPONSE IN GASTROINTESTINAL CANCERS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 51
Abstract
BACKGROUND Carcino Embryonic Antigen (CEA) and Carbohydrate Antigen 19-9 (CA 19-9) were two tumour markers frequently used in the diagnosis, and monitoring of treatment response of gastrointestinal cancers like colon, rectum, stomach, pancreas and gall bladder cancers. MATERIALS AND METHODS This study is a case-control study. 50 diagnosed and confirmed cases of gastrointestinal cancers attending the surgery outpatients department and wards of Jawaharlal Nehru Institute of Medical Sciences, Imphal, Manipur, India from March 2015 to February 2018 form the study group. CEA and CA19-9 estimation was done before the start of any treatment, during treatment and after treatment; may it be Surgery, Radiotherapy or Chemotherapy. The usefulness of these two tumour markers, CEA and CA19-9 combined for monitoring the treatment response was evaluated. RESULTS It is found that the combined use of these two markers CEA and CA19-9 is much more useful for monitoring of treatment response in the patients of gastrointestinal cancers when compared to the use of CEA alone or CA19-9 alone. CONCLUSION It is found that the combined use of these two markers CEA and CA19-9 is much more useful for monitoring of treatment response in the patients of gastrointestinal cancers when compared to the use of CEA alone or CA19-9 alone.
Authors and Affiliations
Rosemary Vumkhoching, Yengkhom Sanatomba Singh, Dhanabir Thangjam, Ningombam Jitendra
Keywords
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- EP ID EP550476
- DOI 10.14260/jemds/2018/1209
- Views 75
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