AMYLOID GOITRE: A RARE CASE STUDY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2013, Vol 2, Issue 51
Abstract
Involvement of the thyroid gland by amyloidosis is a common phenomenon but clinically significant enlargement of the thyroid owing to amyloid deposition is an extremely rare occurrence. Amyloid Goitre is defined as a presence of amyloid within the gland so as to produce a clinically detectable enlargement of the gland1. This is an extremely rare entity, in association with both primary and secondary amyloidosis. Primary amyloidosis occurs spontaneously in the absence of apparent predisposing illness.The diagnosis of amyloid goiter should be considered in any patient with an enlarging diffuse goiter and euthyroid state. Rarely, amyloid goiter may occur as the first sign of systemic amyloidosis. Approximately 200 cases have been reported in English literature. In 50 – 80% of case, it is seen in Medullary carcinoma thyroid2, 3. It is an important etiological factor of End Stage Renal Disease. We describe the clinical and pathological feature of amyloid goiter in a patient which was insidious in onset with no significant influence on thyroid function as seen with the thyroid function tests
Authors and Affiliations
Usharani R, Madhusudhan B. V, Sandeep Patil, Ashok A, Lakkanna S
Keywords
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- EP ID EP95702
- DOI 10.14260/jemds/1709
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