EVALUATION OF CARDIAC ABNORMALITIES IN AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE UTILISING ECHOCARDIOGRAPHY IN THANJAVUR MEDICAL COLLEGE
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 62
Abstract
BACKGROUND Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a multisystem disorder characterised by multiple, bilateral renal cysts associated with cysts in other organs. Non-cystic manifestations of ADPKD involve cardiac valvular abnormalities also, which supports the hypothesis that a defect in extracellular matrix is the basic pathology. The aim of the study is to find out the prevalence of cardiac valvular abnormalities in patients with ADPKD. MATERIALS AND METHODS This was a cross-sectional study conducted in 50 patients admitted with ADPKD over a period of one year in Thanjavur Medical College Hospital. M-mode, 2D echo and Doppler were used to study the valvular abnormalities. RESULTS Out of 50 patients with ADPKD (males- 70% and females- 30%), 24% had MVPS, 36% had MR, 20% had AR and 16% had TR. CONCLUSION Echocardiography is easily performed, noninvasive, safe, reproducible and accurate in assessment of cardiac function in ADPKD. Echocardiographically detectable concentric left ventricular hypertrophy and valvular abnormalities were present in asymptomatic patients. Hence, this necessitates screening of patients without cardiac symptoms for cardiac abnormalities after the diagnosis of ADPKD has been made.
Authors and Affiliations
Nehru D, Vetrivel S, Kannan V. P
Keywords
Related Articles
- EP ID EP228299
- DOI 10.18410/jebmh/2017/750.
- Views 55
- Downloads 0
A RARE CASE OF ACHONDROPLASIA- SHORT LIMB
BACKGROUND A 6-year-old boy was presented to the paediatric department with shortening of all the limbs and delay in growth. Clinical examinations revealed height less than third percentile along with other abnormalities...
PREVALENCE OF BACTERIAL VAGINOSIS IN CASES OF PRETERM LABOUR AND ITS EFFECTS ON OBSTETRIC OUTCOME
BACKGROUND Abnormal vaginal flora is an important cause of preterm labour with subsequent delivery of a preterm newborn, which is associated with significant morbidity and mortality. Bacterial vaginosis is a condition wh...
ENT MANIFESTATIONS IN HEREDITARY HEMORRHAGIC TELANGIECTASIA: A CASE REPORT
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disorder, which affects various internal organs and has a tendency for bleeding. It has a classic triad of mucocutaneous telangiectasias, recurrent hem...
A COMPARATIVE STUDY BETWEEN APACHE II AND RANSON SCORING SYSTEMS IN PREDICTING THE SEVERITY OF ACUTE PANCREATITIS
BACKGROUND Acute pancreatitis is a condition which involves a wide variety of clinical signs and symptom. The course of which ranges from a mild self-limiting inflammatory process to a more fulminant course which could i...
STUDY OF PERIPHERAL SMEARS IN NEONATES
BACKGROUND The haematological parameters in a newborn are distinctly different from the normal adult values. NRBCs are immature RBCs normally seen in the peripheral blood of neonates up to 5 th day of life. At birth, 3 t...