Evaluation of Carotid Intima –Media Thickness in Patients with Chronic Obstructive Pulmonary Disease
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 3
Abstract
Background: Chronic obstructive pulmonary disease [COPD] can be associated with major comorbid diseases including atherosclerosis of blood vessels.Carotid atherosclerosis as characterised by increased intima-media thickness [IMT] is an indicator of atherosclerosis burden and cardiovascular disease risk. Aims: To evaluate the changes of carotid intima-media thickness in patients with chronic obstructive pulmonary disease. To determine the relation between severity of COPD and increased intima-media thickness. Materials and Methods: A case control study was done among 40 patients with COPD and 40 healthy subjects(Aged 50-65yrs) using carotid B mode duplex ultrasonography with high frequency probe (7.5 MHz).Levels more than or equal to 1.2mm was defined as increased IMT.The severity of COPD was assessed by spirometry. An additional risk factor which was studied was plaques in carotid artery. Results: Twenty six patients with COPD and ten from control group had increased Intima-media thickening, which was highly significant[p=0.000]. The relation between severity of COPD and increased IMT was clinically significant but statistically notsignificant[p=.069]. Thirty patients with chronic obstructive pulmonary disease and twelve from control group had increased incidence of soft plaques, which was also highly significant[p =0.000]. Conclusion: Carotid intima media thickness measurement can be effectively used as an early predictor of cardiovascular risk assessment in patients with chronic obstructive pulmonary disease.
Authors and Affiliations
Dr Rajani . M.
Keywords
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